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Coronavirus: Oxford vaccine triggers immune response
A coronavirus vaccine developed by the University of Oxford appears safe and triggers an immune response.
Trials involving 1,077 people showed the injection led to them making antibodies and T-cells that can fight coronavirus.
The findings are hugely promising, but it is still too soon to know if this is enough to offer protection and larger trials are under way.
The UK has already ordered 100 million doses of the vaccine.
The vaccine – called ChAdOx1 nCoV-19 – is being developed at unprecedented speed.
It is made from a genetically engineered virus that causes the common cold in chimpanzees.
It has been heavily modified, first so it cannot cause infections in people and also to make it “look” more like coronavirus.
Scientists did this by transferring the genetic instructions for the coronavirus’s “spike protein” – the crucial tool it uses to invade our cells – to the vaccine they were developing.
This means the vaccine resembles the coronavirus and the immune system can learn how to attack it.
Much of the focus on coronavirus so far has been about antibodies, but these are only one part of our immune defence.
Antibodies are small proteins made by the immune system that stick onto the surface of viruses.
Neutralising antibodies can disable the coronavirus.
T-cells, a type of white blood cell, help co-ordinate the immune system and are able to spot which of the body’s cells have been infected and destroy them.
Nearly all effective vaccines induce both an antibody and a T-cell response.
Levels of T-cells peaked 14 days after vaccination and antibody levels peaked after 28 days. The study has not run for long enough to understand how long they may last, the study in the Lancet showed.
Prof Andrew Pollard, from the Oxford research group told the BBC: “We’re really pleased with the results published today as we’re seeing both neutralising antibodies and T-cells.
“They’re extremely promising and we believe the type of response that may be associated with protection.
“But the key question everyone wants to know is does the vaccine work, does it offer protection… and we’re in a waiting game.”
The study showed 90% of people developed neutralising antibodies after one dose. Only ten people were given two doses and all of them produced neutralising antibodies.
“We don’t know the level needed for protection, but we can maximise responses with a second dose,” Prof Pollard told the BBC.
Yes, but there are side-effects.
There were no dangerous side-effects from taking the vaccine, however, 70% of people on the trial developed either fever or headache.
The researchers say this could be managed with paracetamol.
- BBC
The Africa Investment Network has entered a new partnership with 17 Asset Management to expand investment opportunities for Africans in the diaspora.
The two organisations will work together to open more pathways for diaspora investors, provide better data on markets, and connect investors to viable projects across the continent.
The partnership will focus on mapping investment opportunities across countries and sectors, building a Diaspora Pathways Program to guide new investors, and creating a shared research platform that provides market insights, returns benchmarks, regulatory updates and sector outlooks.
The two groups will also develop a trade and deal catalogue to help match businesses with partners.
As part of the collaboration, both institutions will host investment roadshows through the Global Africa Summit series, starting with GAS Accra from December 11 to 12 at the Alisa Hotel.
The event will showcase deals, hold sector briefings and connect investors with government and private sector actors.
Africa Investment Network founder and Chief Executive Jane Reindorf Osei noted that diaspora capital remains one of Africa’s strongest advantages because it is patient, purpose driven and closely linked to local development outcomes.
She explained that the partnership will help direct more diaspora investment into areas where it can make the most impact.
Chairman of 17 Asset Management, John Morris, highlighted that the joint effort will blend strong investment design with Africa Investment Network’s networks and convening power.
He stressed that improved research and compliant market access will give diaspora investors more confidence across different markets.
The two institutions will open their diaspora investment platform in the second quarter of 2026, followed by the launch of a co investment window.
Investment roadshows will also be held in North America, the Caribbean and key African centres next year.
Africa Investment Network and 17 Asset Management invited governments, development finance institutions, family offices, asset managers and other partners to support deal creation, risk sharing and market building initiatives aimed at boosting diaspora participation.
By: Jacob Aggrey
Government Communications Minister Felix Kwakye Ofosu insists that neither President Mahama nor the National Democratic Congress has filed any petition seeking the removal of the Electoral Commission Chairperson and her two deputies.
In a one on one Interview with GHone, he explained that the President only forwarded petitions he received, as required by law, and has not initiated any action against the EC leadership.
According to him, the identities and motives of the petitioners remain unknown to government, and the Presidency is not involved in that part of the process.
Mr Kwakye Ofosu stressed that while the NDC has openly disagreed with some actions of the Electoral Commission in the past, the party has not submitted any petition asking for the removal of the EC Chair or her deputies.
He noted that comments by the NDC National Chairman, Johnson Asiedu Nketiah, questioning the EC’s competence, do not amount to a formal petition.
He added that criticism of public officials is normal and does not automatically translate into a request for their removal.
Mr Kwakye Ofosu explained that once a petition is received, the President’s only role is to forward it to the Chief Justice.
The Chief Justice then decides if the allegations have merit. If they do, a committee is set up to investigate.
He said those named in the petitions will be officially informed by the Chief Justice, not the Presidency.
They will then have the opportunity to appear before the committee, respond to the claims, and provide any evidence in their defence.
Mr Kwakye Ofosu expressed confidence that the process will be fair and will protect the rights of all those involved.
By: Jacob Aggrey
