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Coronavirus: Oxford vaccine triggers immune response

A coronavirus vaccine developed by the University of Oxford appears safe and triggers an immune response.
Trials involving 1,077 people showed the injection led to them making antibodies and T-cells that can fight coronavirus.
The findings are hugely promising, but it is still too soon to know if this is enough to offer protection and larger trials are under way.
The UK has already ordered 100 million doses of the vaccine.
The vaccine – called ChAdOx1 nCoV-19 – is being developed at unprecedented speed.
It is made from a genetically engineered virus that causes the common cold in chimpanzees.
It has been heavily modified, first so it cannot cause infections in people and also to make it “look” more like coronavirus.
Scientists did this by transferring the genetic instructions for the coronavirus’s “spike protein” – the crucial tool it uses to invade our cells – to the vaccine they were developing.
This means the vaccine resembles the coronavirus and the immune system can learn how to attack it.
Much of the focus on coronavirus so far has been about antibodies, but these are only one part of our immune defence.
Antibodies are small proteins made by the immune system that stick onto the surface of viruses.
Neutralising antibodies can disable the coronavirus.
T-cells, a type of white blood cell, help co-ordinate the immune system and are able to spot which of the body’s cells have been infected and destroy them.
Nearly all effective vaccines induce both an antibody and a T-cell response.
Levels of T-cells peaked 14 days after vaccination and antibody levels peaked after 28 days. The study has not run for long enough to understand how long they may last, the study in the Lancet showed.
Prof Andrew Pollard, from the Oxford research group told the BBC: “We’re really pleased with the results published today as we’re seeing both neutralising antibodies and T-cells.
“They’re extremely promising and we believe the type of response that may be associated with protection.
“But the key question everyone wants to know is does the vaccine work, does it offer protection… and we’re in a waiting game.”
The study showed 90% of people developed neutralising antibodies after one dose. Only ten people were given two doses and all of them produced neutralising antibodies.
“We don’t know the level needed for protection, but we can maximise responses with a second dose,” Prof Pollard told the BBC.
Yes, but there are side-effects.
There were no dangerous side-effects from taking the vaccine, however, 70% of people on the trial developed either fever or headache.
The researchers say this could be managed with paracetamol.
- BBC
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Prof Alidu Seidu files nomination for Tamale Central seat

The newly elected parliamentary candidate of the National Democratic Congress (NDC) for Tamale Central, Prof Alidu Seidu, has submitted his nomination forms to the Electoral Commission.
As of 10:00 a.m. today, he was the only person who had filed to contest the seat.
Nomination of candidates will close at the end of the day.
Associate Professor and Head of the Political Science Department at the University of Ghana Legon, Prof. Alidu Seidu won the National Democratic Congress (NDC) parliamentary primaries in the Tamale Central constituency with a landslide victory.
The elections, supervised by the party’s Elections and IT Directorate in the Northern Region, saw Prof. Seidu poll 840 votes out of the total valid ballots cast.
His closest contender, Lawyer Hanan Gundadow Abdul-Rahaman, secured 536 votes.
The other aspirants could not make significant gains, with Dr. Seidu Fiter obtaining 44 votes, Aliu Abdul-Hamid 23 votes, and the rest recording fewer than 10 votes each.
In all, 1,500 ballots were cast, with 6 ballots rejected and 7 spoilt ballots recorded.
The results were signed and declared by Dr. Arnold Mashud Abukari, NDC Northern Regional Director of Elections and IT.
The National Democratic Congress (NDC) held parliamentary primaries in Tamale Central to choose a candidate for the upcoming by-election following the death of the sitting Member of Parliament, Dr. Ibrahim Murtala Mohammed. Dr. Mohammed, who also served as Minister for Environment, Science, Technology and Innovation, tragically died in a military helicopter crash in the Adansi Akrofuom District on August 6, 2025, alongside seven others.
His passing left the Tamale Central seat vacant, as required by Ghana’s 1992 Constitution.
The Electoral Commission has scheduled the by-election for September 30, 2025. While the NDC moved quickly to open nominations and vet aspirants, the New Patriotic Party (NPP) announced it would not contest the seat, citing the need to respect the somber circumstances and promote national unity.
By: Jacob Aggrey
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Ghana to locally refine its gold starting October 2025 – Sammy Gyamfi

The Chief Executive Officer of the Ghana Gold Board, Sammy Gyamfi, has announced that plans are far advanced for the establishment of a state-owned gold refinery in the country.
Speaking at the 2025 Minerals and Mining Convention, Mr Gyamfi said the refinery will process locally mined gold into bullion instead of exporting it in its raw state.
According to him, it is unacceptable that Ghana, despite being a leading gold producer in Africa, continues to export raw gold known as dore.
He explained that the Gold Board, working with the Bank of Ghana and local refineries, will from October 2025 begin refining gold locally.
He also disclosed that an ultramodern assay laboratory will be built to ensure international standards in testing gold quality.
Mr Gyamfi noted that the refinery will be wholly state-owned and will help Ghana move away from raw mineral exports to value addition.
This, he said, will boost foreign exchange earnings, create jobs, and position Ghana as a hub for gold refining and jewellery production in Africa.
The CEO stressed that the project forms part of government’s strategy to ensure the country benefits fully from its natural resources and to transform the mining sector into a driver of economic growth.
By: Jacob Aggrey