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Coronavirus: Oxford vaccine triggers immune response
A coronavirus vaccine developed by the University of Oxford appears safe and triggers an immune response.
Trials involving 1,077 people showed the injection led to them making antibodies and T-cells that can fight coronavirus.
The findings are hugely promising, but it is still too soon to know if this is enough to offer protection and larger trials are under way.
The UK has already ordered 100 million doses of the vaccine.
The vaccine – called ChAdOx1 nCoV-19 – is being developed at unprecedented speed.
It is made from a genetically engineered virus that causes the common cold in chimpanzees.
It has been heavily modified, first so it cannot cause infections in people and also to make it “look” more like coronavirus.
Scientists did this by transferring the genetic instructions for the coronavirus’s “spike protein” – the crucial tool it uses to invade our cells – to the vaccine they were developing.
This means the vaccine resembles the coronavirus and the immune system can learn how to attack it.
Much of the focus on coronavirus so far has been about antibodies, but these are only one part of our immune defence.
Antibodies are small proteins made by the immune system that stick onto the surface of viruses.
Neutralising antibodies can disable the coronavirus.
T-cells, a type of white blood cell, help co-ordinate the immune system and are able to spot which of the body’s cells have been infected and destroy them.
Nearly all effective vaccines induce both an antibody and a T-cell response.
Levels of T-cells peaked 14 days after vaccination and antibody levels peaked after 28 days. The study has not run for long enough to understand how long they may last, the study in the Lancet showed.
Prof Andrew Pollard, from the Oxford research group told the BBC: “We’re really pleased with the results published today as we’re seeing both neutralising antibodies and T-cells.
“They’re extremely promising and we believe the type of response that may be associated with protection.
“But the key question everyone wants to know is does the vaccine work, does it offer protection… and we’re in a waiting game.”
The study showed 90% of people developed neutralising antibodies after one dose. Only ten people were given two doses and all of them produced neutralising antibodies.
“We don’t know the level needed for protection, but we can maximise responses with a second dose,” Prof Pollard told the BBC.
Yes, but there are side-effects.
There were no dangerous side-effects from taking the vaccine, however, 70% of people on the trial developed either fever or headache.
The researchers say this could be managed with paracetamol.
- BBC
Madam Sandra Seyram Kpedor, the District Chief Executive (DCE) of Anloga in the Volta Region, has emphasised the importance of parental involvement in children’s education, stating that education is free, but parents need to do more to support their children.
She said parents, teachers, and students must be involved in addressing the challenges facing the district’s education sector, particularly the poor Basic Education Certificate Examination (BECE) results.
Madam Kpedor outlined some key roles parents should play to promote their children’s education, including providing a conducive learning environment, monitoring their children’s progress, and supporting teachers.
The DCE highlighted some challenges the district faced such as inadequate infrastructure and a shortage of teachers, which have also contributed to the poor BECE results and called on well-to-do parent to help solve the situation through and other supports.
To address the issues, she also announced that plans have been taken to utilise the district’s common fund to implement educational projects, such as constructing school blocks and teachers’ bungalows at Sodzi community, and 2-unit classroom blocks each at Akplorwutorkor and Tegbi-Afedome respectively, among others.
Madam Kpedor also noted that her office had earlier notified the Ministry of Education to deploy more teachers to the area to improve teaching and learning, and encouraged students to work hard and strive for excellence, and work beyond their limit to succeed.
“To my wonderful and beautiful girls, you have to know it clear that women and girls have equal opportunities to compete with men for greater achievements,” she indicated.
The DCE cited her own achievement as a testament to the fact that women can excel in leadership positions, alongside Vice President Nana Jane Opoku-Agyemang, and stressed that girls were no longer limited to domestic roles but can pursue their dreams and become leaders.
Additionally, she mentioned that a meeting was held earlier with assembly members, and other stakeholders to address the district’s educational challenges and improve academic performance.
She promised that the district’s education oversight committee and stakeholders would work together to address the challenges and improve the district’s BECE results and called for parental involvement and support to boost the district’s education sector for children to chase their dreams to become future leaders for the success of the district and the nation.
She urged parents not to leave everything to the government but rather help in the provision of some necessary materials such as textbooks, exercise books, pens, pencils, food, and guidance to children for the successes of young learners. –GNA
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The spokesperson for Dr. Bawumia, Dennis Miracles Aboagye, has criticised the implementation of the NDC government’s No Fee Stress policy, arguing that the programme has failed to deliver on its core promise.
According to him on Starr fm, the policy, which was introduced to ensure stress free payment of fees for level 100 tertiary students, has rather turned into what he described as post stress support.
He explained that students are required to pay their fees first before applying for reimbursement, a situation he believes defeats the purpose of the policy.
He questioned claims by government officials that the policy has been successful and that citizens are happy.
In his view, such claims do not reflect the lived realities of many Ghanaians. He stressed that while some people may appear satisfied, many others continue to struggle.
Dennis Miracles Aboagye pointed to the situation of trained teachers and nurses who have been picketing for nearly six months, demanding employment.
He noted that government responses suggesting it cannot accommodate all of them contradict claims of economic stability.
He further argued that economic indicators such as a stable currency mean little to people who are unable to secure jobs or access promised support.
He observed that telling an unemployed teacher or a struggling student that the cedi has strengthened does not address their immediate challenges.
On the issue of tertiary education, he maintained that no level 100 student benefited from stress free fees in 2025, despite the policy being announced.
He added that in 2026, students have already reported to school without receiving the promised support.
He insisted that asking students to pay fees first and seek reimbursement later amounts to support after hardship, not stress free education.
According to him, this approach goes against what was promised during the policy announcement.
Dennis Miracles Aboagye questioned why a government that presents the economy as strong is unable to fulfil what he described as simple and clear promises.
He added that there is a fundamental problem with the way the economy is being managed and indicated that he is prepared to explain his position further.
By: Jacob Aggrey
