Features
The role of Telomeres in the lifespan of men and women
TELOMERES, the protective caps on the ends of chromosomes, play a crucial role in maintaining genomic stability and regulating cellular aging.
The length of telomeres has been associated with lifespan and age-related diseases, with recent studies highlighting sex differences in telomere biology.
This article provides a comprehensive review of the current knowledge on the role of telomeres in the lifespan of men and women, highlighting the physiological and molecular mechanisms underlying these differences.
Introduction
Telomeres are repetitive nucleotide sequences (TTAGGG in humans) that cap the ends of chromosomes, protecting them from deterioration and fusion. Telomere length (TL) shortens with each cell division, and when TL reaches a critical threshold, cells enter senescence or undergo programmed cell death (apoptosis).
Telomere shortening has been implicated in aging and age-related diseases, including cardiovascular disease, cancer, and dementia.
Sex differences in telomere length
Women generally have longer telomeres than men, with a slower rate of telomere shortening with age.
A study published in the Journal of the American Medical Association (JAMA) found that women had longer telomeres than men across all age groups.
This sex difference in TL is thought to contribute to the female advantage in lifespan, with women living approximately 5–7 years longer than men on average.
Mechanisms underlying sex differences in telomere length
- Estrogen: Estrogen has been shown to increase telomerase activity, the enzyme responsible for maintaining TL, in human cells. Estrogen also has antioxidant properties, reducing oxidative stress and inflammation, which contribute to telomere shortening.
- Genetic Factors: Genetic variants in telomere-related genes, such as TERT (telomerase reverse transcriptase), have been associated with TL and lifespan. A study published in Nature found that genetic variants in TERT were associated with TL and risk of age-related diseases.
- Lifestyle Factors: Lifestyle factors, such as smoking, physical activity, and diet, can influence TL, with women generally exhibiting healthier lifestyle habits.
Telomere shortening and age-related diseases
Telomere shortening has been implicated in various age-related diseases, including:
- Cardiovascular Disease: Short TL has been associated with increased risk of cardiovascular disease, including myocardial infarction and stroke.
- Cancer: Telomere shortening is a hallmark of cancer, with cancer cells often exhibiting critically short TL.
- Dementia: Short TL has been associated with increased risk of dementia, including Alzheimer’s disease.
Sex differences in telomere shortening and age-related diseases
Women tend to have a slower rate of telomere shortening with age, which may contribute to their lower risk of age-related diseases.
A study published in the Journal of the American Geriatrics Society found that women had a slower rate of telomere shortening and lower risk of age-related diseases compared to men.
Clinical implications
- Telomere Length as a Biomarker: TL has been proposed as a biomarker for aging and age-related diseases, with potential applications in clinical practice.
- Telomere-Targeted Therapies: Therapies aimed at maintaining or increasing TL, such as telomerase activators, are being explored for the treatment of age-related diseases.
Conclusion
Telomeres play a critical role in regulating cellular aging, with sex differences in TL contributing to the female advantage in lifespan. Understanding the mechanisms underlying these differences is essential for developing effective prevention and treatment strategies for age-related diseases.
Let’s dive deeper into the topic of telomeres and their role in aging.
What are telomeres?
Telomeres are repetitive DNA sequences (TTAGGG in humans) that cap the ends of chromosomes, protecting them from deterioration and fusion. Think of them like the plastic tips on shoelaces, preventing the chromosomes from unraveling.
How do telomeres affect aging?
- Telomere Shortening: Each time a cell divides, its telomeres shorten. When telomeres become too short, the cell can no longer divide and becomes senescent or undergoes apoptosis (programmed cell death).
- Aging and Telomeres: Telomere shortening is associated with aging and age-related diseases, such as cardiovascular disease, cancer, and dementia.
Sex differences in telomere length
- Women have longer telomeres: Women generally have longer telomeres than men, which may contribute to their longer lifespan.
- Estrogen’s role: Estrogen has been shown to increase telomerase activity, the enzyme responsible for maintaining telomere length, which may explain why women have longer telomeres.
Factors influencing Telomere length
- Genetics: Genetic variants in telomere-related genes can affect telomere length.
- Lifestyle: Factors like smoking, physical activity, and diet can influence telomere length.
- Stress: Chronic stress can lead to telomere shortening.
Telomeres and age-related diseases
- Cardiovascular Disease: Short telomeres are associated with increased risk of cardiovascular disease.
- Cancer: Telomere shortening is a hallmark of cancer.
- Dementia: Short telomeres are associated with increased risk of dementia.
Potential Applications
- Biomarker for aging: Telomere length could serve as a biomarker for aging and age-related diseases.
- Telomere-Targeted Therapies: Therapies aimed at maintaining or increasing telomere length are being explored for age-related diseases.
BY ROBERT EKOW GRIMMOND THOMPSON
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Features
The harvest of shame: Why production without protection is crushing the Ghanaian farmer
In late 2025 and early 2026, Ghana witnessed a cruel paradox. From Tumu in the Upper West Region to Akomadan in Ashanti Region and Ziope in the Volta Region, farmers harvested abundance only to watch it rot.
This food glut occurred where thousands of bags of maize, rice, tomatoes, crates of eggs and other foodstuffs remain unsold, even as consumers especially in the urban areas complained bitterly about soaring food prices. In Ghana today, success in farming has become a punishment.
Here is the hard truth: Ghana’s food crisis is no longer about how much we produce; it is about how poorly we protect, move, price, and value what we produce. Until we build and fix storage, market rules, processing capacity, and import discipline, bumper harvests will keep bankrupting farmers while cities keep paying too much.
Over the last decade, national policies have celebrated production. Initiatives like “Planting for Food and Jobs” (PFJ) and “Nkoko Nkitinkiti” expanded acreage, inputs, and output. By most metrics, farmers delivered.
Yet the food system beyond the farm gate (storage, transport, processing, pricing, and trade protection) was left to chance.
The result is a broken chain. A maize farmer in the Upper West sells a 100kg bag for about GH¢200, down from GH¢500 the previous year, a 60% collapse.
In Accra, maize products barely reflect this drop. Poultry farmers offload eggs at GH¢40 per crate, while consumers still pay GH¢75. Somewhere between farm and market, value is extracted, distorted, and hoarded.
Reports across food markets show that the greatest margins sit not with producers, but with intermediaries also known as “middlemen”. High transport costs, multiple informal levies, weak farmer bargaining power, and opaque pricing allow middlemen to buy at giveaway prices and sell at premiums. This has led to farmers being financially crippled, unable to recover input costs or reinvest for the next season. Young investors are also discouraged from agriculture due to the little to no profits or negative margins.
Consumers remain trapped in high-price markets despite national food surpluses. Ghana has mastered the art of growing food, but failed at the science of managing it.
Import dependence is also another factor undermining local success. While imports can stabilize prices during shortages, Ghana’s current trade posture actively undermines local producers. The appreciation of the cedi in 2025–2026 made imported rice, poultry, onions, and tomato paste cheaper just as local harvests peaked.
Tomato farmers in Akomadan and Ziope watched their produce decay as markets preferred longer-shelf-life varieties from Burkina Faso or imported paste. Poultry farmers struggle against frozen chicken imports. This is not competition; it is policy neglect.
The impact of these actions will be felt when local farmers lose market confidence and reduce future production, where Ghana exports jobs and value while importing food insecurity and end up sacrificing its long-term food sovereignty for short-term price optics. True food security comes from stable local prices and resilient producers, not volatile imports that collapse domestic systems.
Some argue that imports are necessary to protect the urban poor and keep inflation low. This is partially true but dangerously incomplete. Cheap imports may ease prices today, but they destroy the producer base that feeds the nation tomorrow. Without seasonal import controls, border discipline, and anti-smuggling enforcement, Ghana is locking itself into perpetual dependence and rural poverty.
A protection package Ghana can implement
If abundance is to become prosperity, Ghana must pivot from a production-only mindset to full value-chain protection:
1. Guaranteed minimum price + strategic buffer buying (MoFA/NAFCO/GGC): During peak harvest, the state and credible private aggregators should buy key staples at a floor price based on transparent quality grades. The rule should be clear: when prices fall below a threshold, the buffer buyer steps in; quickly, transparently, and with audit trails.
2. Storage and cold-chain as national infrastructure, not an afterthought (MoTI, MoFA, Assemblies, private sector): Every major producing corridor should have community aggregation centres, warehouse capacity with grading and weighing, cold rooms for perishables including solar-backed cold storage where feasible.
3. Rules-based seasonal import controls (MoTI, Customs, enforcement agencies): Ghana should define import windows for selected commodities, set clear triggers and enforce controls during peak harvest periods.
4. Institutional procurement that guarantees demand (GES/School Feeding, Prisons Service, Hospitals, Security Services): Set district-level procurement targets and mandate institutions to source food locally, especially in harvest seasons. This creates predictable demand, supports farm prices and improves nutrition quality in public institutions.
5. Market transparency and farmer power (digital price dashboards + cooperatives + enforceable contracts): Farmers must have resources like real-time price information by region, standard grading and weights, contract farming frameworks with dispute mechanisms and strengthened cooperatives that negotiate transport, storage, and sales. These resources reduce dependence on exploitative intermediation. When farmers act individually, they are easy to squeeze. When they aggregate, they can bargain.
One more thing: stop treating value addition as a slogan. The promise of “One District One Factory” vision must move beyond political slogans and become the “One District One Processing Plant” reality for our perishable staples.
A bumper harvest should be a cause for national celebration, not financial death sentence to the farmer. Until Ghana fixes the space between the farm and the fork, abundance will remain a curse and the Ghanaian farmer will keep paying the price for feeding the nation.
By: Sophia Komasi
Features
On Ghanaian migrants in Finland, Ghana’s 69th independence anniversary

The Ghanaian community in Finland on Saturday, March 14, 2026, celebrated Ghana’s 69th independence anniversary in an impressive event in Helsinki, the capital city of Finland.
The event was organised by the Ghana Union Finland (GUF), an association of Ghanaian migrants in Finland. It was an occasion well attended by many people from the Ghanaian community in Finland, Finns and other nationalities.
The occasion was graced by the Special Guest, Her Excellency Abigail Naa Adzoko Kwashi, the Ambassador of Ghana to Norway with concurrent accreditation to Finland and Iceland.
In her speech, the Ambassador encouraged Ghanaians living in Finland to pursue unity, actively participate in, and support the Ghana Union Finland to build a stronger body better positioned to advocate for its interests and goals.
Also present at the event was the Honorary Consul of Ghana in Finland, Mrs Kati Kivisaari, who has replaced the retired Ms Ulla Alanko. Mrs Kivisaari urged Ghanaians in Finland to remain good ambassadors of Ghana in their lives in Finland.
The event saw the inauguration of new executive members of the Ghana Union Finland. The team was inducted by Elder Samuel Anini, Patron of the Ghana Union Finland.
Earlier, a “royal entry” was performed by leaders of the Asanteman Finland and Mfantseman Kuw and other personalities in their colourful kente attire adorned with ornaments, amidst traditional music and adowa dance to usher in the Ambassador.
Some personalities present at the event were Nana Ekuoba Gyasi Gyimah and other leaders of Asanteman Finland, Mfantseman Kuw Finland, as well as representatives of other Ghanaian ethnic groups.
It was a very colourful occasion with dance and other performances such as poetry recitals. The audience was also treated to tasty Ghanaian dishes such as jollof rice, fried yam, and soft drinks.
Unity and harmony
I see such events, especially the ones marking independence anniversaries, as ample display of unity and harmony in the Ghanaian migrant community as well as in the larger Ghana and Finland relations.
For me personally, whenever I think about Ghana’s Independence Day anniversary every 6th of March, my mind also goes to Finland’s own day on 6th of December. The two dates always give me such a special, positive feeling. As soon as one of the dates ends, I begin a countdown to the other (next) date.
Last year on December 6, 2025 when Finland celebrated its 108th independence anniversary and I participated in two events marking the celebration in Helsinki, I started looking forward to Ghana’s 69th anniversary this year. Now that Ghana’s anniversary is over, I am looking forward to Finland’s 109th anniversary on December 6, 2026. That’s the beauty of it all for me.
Ensuring integration
What I see in all this, especially for Ghanaian migrants in Finland, is the chance for members of the Ghanaian diaspora in Finland to integrate into the Finnish society through such celebrations that are marked by social activities, affiliations and ideas of inclusion.
Inclusion is key to integration, and the two ideas undoubtedly build a sense of belonging. As I previously wrote, Finland sees the role of migrant associations as bridge-builders for the integration and inclusion of migrants through participation in the decision making process and by acting as a representative voice, which is highly appreciated in Finland.
As I keep pointing out, Finland encourages migrants’ participation in the planning of issues concerning the migrants themselves, using such a strategy as one of the efficient ways to improve their inclusion. Thus, there is an enabling environment created within the Finnish cultural ecology that undoubtedly helps migrants to integrate into the host Finnish society. Thank you!
GHANA MATTERS COLUMN
With Dr Perpetual Crentsil



