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Malaria pill trialed to prevent COVID-19

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A trial to see whether two anti-malarial drugs could prevent COVID-19 has begun in Brighton and Oxford.
Chloroquine, hydroxychloroquine or a placebo will be given to more than 40,000 healthcare workers from Europe, Africa, Asia and South America.
All the participants are staff who are in contact with COVID-19 patients.
US President Donald Trump was criticised this week after he said he had been taking hydroxychloroquine, despite warnings it might be unsafe.
The first UK participants in the global trial were enrolled yesterday at the Brighton and Sussex University Hospitals and the John Radcliffe Hospital in Oxford.
They will be given either hydroxychloroquine or a placebo for three months. At sites in Asia, participants will be given chloroquine or a placebo.
These are the first of a planned 25 UK sites, with results expected by the end of the year.
The trial is open to anyone delivering direct care to coronavirus patients in the UK, as long as they have not been diagnosed with COVID-19.
It will test whether the drugs can prevent healthcare workers exposed to the virus from contracting it.
One of the study’s leaders, Prof Nicholas White at the University of Oxford said: “We really do not know if chloroquine or hydroxychloroquine are beneficial or harmful against COVID-19.”
But, he said, a randomised controlled trial such as this one, where neither the participant nor the researchers know who has been given the drug or a placebo, was the best way to find out.
“A widely available, safe and effective vaccine may be a long way off,” said Prof Martin Llewelyn from Brighton and Sussex Medical School, who is also leading the study.
“If drugs as well-tolerated as chloroquine and hydroxychloroquine could reduce the chances of catching COVID-19, this would be incredibly valuable.”
The drugs can reduce fever and inflammation and are used as both a prevention and a treatment for malaria.
Hydroxychloroquine regulates the body’s immune response and is also used in the treatment of rheumatoid arthritis and Lupus – an inflammatory disease caused by an overactive immune system.
Lupus charities in the UK and US have raised concerns that demand for the drug associated with coronavirus could threaten the supply for patients who already rely on it. -BBC
News
“Nobody can unite NPP better than Afoko”

Private Legal Practitioner and New Patriotic Party (NPP) stalwart Charles Owusu Juanah says Awentami Paul Afoko has already started engaging members of opposing camps within the party as part of efforts to build a united front ahead of the 2028 elections.
Lawyer Juanah, who is the National Chairman of Friends of Bawumia, said some NPP members who have lost key positions have become disgruntled and now behave as though the party belongs to them.
He said this attitude has contributed to the divisions within the party and created the need for a leadership figure capable of bringing the various groups back together.
Juanah believes Afoko has the personality and relationships necessary to undertake that reconciliation.
He revealed that the former chairman has already started reaching out to people from opposing camps.
“He has even begun interacting with opposing camps in order to form a united front ahead of the 2028 elections,” Juanah said.
According to him, Afoko’s engagement with rival groups shows his focus is on building the party rather than deepening existing divisions.
Juanah said the former chairman understands that the NPP cannot successfully prepare for the next election while its members remain divided.
“He has foresight, the vision, and strategy to ensure there’s a united front,” he said.
Juanah added that Afoko had already begun talks with some members as part of the process.
He said these engagements demonstrate a willingness to listen to different sides and create a platform where members who have fallen out with one another can work together.
“He has even begun talks with some members,” Juanah said.
He argued that Afoko’s approach also shows his understanding of leadership.
According to Juanah, leadership in the current circumstances requires someone who can speak to different factions without treating political disagreements as permanent divisions.
He said Afoko’s charisma allows him to engage people who may not belong to the same camp.
Juanah therefore believes the former chairman can help bring back members who feel alienated from the party.
“If there’s anyone who can ensure all disgruntled members come together, then it’s no other than Paul Afoko,” he said.
For Juanah, the reconciliation effort is important because the NPP will need a united internal structure before it can effectively organise for the 2028 election. He said Afoko’s current engagement with rival camps is therefore consistent with the former chairman’s broader “Reunite, Rebuild, and Recapture” message.
By: Jacob Aggrey
News
Maiden Black Star Fashion Week to highlight Ghana’s National Fashion Platform

Ghana is set to take centre stage in fashion, culture and the creative economy as the maiden Black Star Fashion Week (BSFW) takes off with a two-day national fashion experience designed to discover talent, convene the industry and showcase Ghanaian fashion on a global stage.
Put together by the Presidency-backed Black Star Experience Secretariat led by Rex Owusu Marfo, with support from the Ministry of Tourism, Culture and Creative Arts and its agencies such as the Ghana Tourism Authority (GTA) and Creative Arts Agency, it is structured across two connected experiences in Accra and Senchi.
The Black Star Fashion Week will move from inteligent industry dialogue and talent discovery to an exciting fashion celebration.
The first day will take place in Accra on November 4 and will centre on the Black Star Fashion Summit.
The Summit will bring together designers, fashion entrepreneurs, creatives, industry leaders, investors, buyers, manufacturers, policymakers, media and other stakeholders for a day of conversations, knowledge exchange, networking and talent development.
The Accra experience will feature keynote addresses, panel discussions, fireside conversations, masterclasses, industry presentations and practical workshops covering areas relevant to the growth of Ghana’s fashion industry, including entrepreneurship, branding, digital marketing, textile innovation, manufacturing, fashion finance, export readiness, e-commerce, artificial intelligence, sustainability and intellectual property.
A major component of Day One will be the 16-Region Designer Programme, bringing emerging fashion talent from across the country into one national platform.
Each participating designer will present a creative interpretation of their region, reflecting its identity, culture, heritage, materials, craftsmanship and contemporary design language.
The Accra programme will culminate in the selection of five designers. Out of the five, one will advance to the flagship fashion show at Senchi.
The second day will move to Royal Senchi on November 7, where the Black Star Fashion Show and experience will take place.
Beyond the runway, Senchi will host a Fashion Village, bringing together designer showcases, retail, textiles, artisan experiences, brand activations, beauty, technology, food and beverage, tourism and lifestyle experiences.
The event will also celebrate Ghana’s cultural diversity through music, dance, textiles, craft, food, storytelling, heritage and visual arts, demonstrating the deep connection between fashion and Ghana’s wider cultural ecosystem.
Honours will go out to outstanding contributors to Ghana’s fashion ecosystem, while networking and business engagements will connect designers and creative businesses with buyers, investors, manufacturers, retailers and other industry stakeholders.
Black Star Experience (BSE) is a Government of Ghana inititive for Culture, Arts, Tourism and Creative engagement.
As a national, year-round platform, the Black Star Experience brings together Ghana’s cultural, artistic, tourism and creative offerings to strengthen Ghana’s identity, promote the country as a preferred global destination and position Ghana as a leading cultural and creative capital of Africa.




