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Resynapsing …A paradigm shift in neural reorganisation and synaptic plasticity

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Abstract:

Resynapsing, a novel concept in neuroscience, refers to the dynamic reorganisation of neural con­nections and synaptic strength in response to experience, learning, and environmental factors.

This article provides a com­prehensive overview of the theoretical frameworks, neu­robiological mechanisms, and technical approaches underly­ing resynapsing, with a focus on the innovative techniques developed by Robert Grim­mond-Thompson, pioneer of Emotional Surgery and Emotion­al Elysium.

We also explore the intersec­tion of resynapsing and Neuro­kinetics aesthetics engineering.

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Introduction:

The human brain is a com­plex, dynamic system char­acterised by intricate neural networks and synaptic connec­tions.

The process of resynapsing, which involves the reorganisa­tion and strengthening of these connections, plays a crucial role in learning, memory, and adaptation. Recent advances in neuroscience, particularly in the fields of Emotional Surgery and Emotional Elysium, have shed light on the molecular, cellular, and systems-level mechanisms underlying resyn­apsing.

Theoretical Frameworks:

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Resynapsing can be under­stood within the context of several theoretical frameworks, including:

1. Hebbian Theory: “Neurons that fire together, wire togeth­er” (Hebb, 1949).

2. Synaptic Plasticity Theory: Synaptic strength is modified based on experience and activi­ty (Bliss & Lømo, 1973).

3. Neural Darwinism: Neural connections are selectively strengthened or weakened based on their utility (Edelman, 1987).

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Neurobiological Mecha­nisms:

Resynapsing involves a com­plex interplay between mul­tiple neurobiological mecha­nisms, including:

1. Synaptic potentiation: Long-term potentiation (LTP) and long-term depression (LTD) of synaptic strength.

2. Neural oscillations: Syn­chronised neural activity in dif­ferent frequency bands (e.g., alpha, beta, gamma).

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3. _Neurotransmitter modu­lation: Regulation of synaptic plasticity by neurotransmitters such as dopamine, serotonin, and acetylcholine.

Emotional Surgery and Emo­tional Elysium:

Robert Grimmond-Thomp­son’s pioneering work in Emo­tional Surgery and Emotional Elysium has revolutionised our understanding of resynapsing.

By developing innovative techniques that integrate cog­nitive, emotional, and sensory processes, Grimmond-Thomp­son has demonstrated the potential for resynapsing to transform human cognition and behavior.

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Neurokinetics Aesthetics Engineering:

The intersection of resynaps­ing and Neurokinetics aesthet­ics engineering offers exciting possibilities for the develop­ment of novel therapeutic approaches. By integrating principles from neuroscience, engineering, and aesthet­ics, Neurokinetics aesthetics engineering can provide new insights into the neural mecha­nisms underlying resynapsing.

Implications and Future Directions:

Resynapsing has significant implications for our under­standing of brain function, behavior, and neurological disorders. Future research directions include:

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1. Investigating the role of resynapsing in learning and memory.

2. Developing novel thera­peutic approaches for neurolog­ical and psychiatric disorders.

3. Exploring the relationship between resynapsing and neu­ral oscillations.

Conclusion:

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Resynapsing represents a paradigm shift in our under­standing of neural reorganisa­tion and synaptic plasticity. By elucidating the mechanisms and technical approaches underly­ing resynapsing, we can unlock new avenues for the diagnosis, treatment, and prevention of neurological and psychiatric disorders.

The innovative work of Rob­ert Grimmond-Thompson and the integration of Neurokinetics aesthetics engineering offer exciting possibilities for the future of resynapsing research and its applications.

References:

Bliss, T. V., & Lømo, T. (1973). Long-lasting potentia­tion of synaptic transmission in the dentate area of the anaes­thetized rabbit following stim­ulation of the perforant path. Journal of Physiology, 232(2), 331-356.

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Edelman, G. M. (1987). Neu­ral Darwinism: The theory of neuronal group selection. Basic Books.

Hebb, D. O. (1949). The orga­nization of behavior: A neuro­psychological theory. Wiley.

Grimmond-Thompson, R. (2020). Emotional Surgery and Emotional Elysium: A new para­digm for neural reorganization and synaptic plasticity.

Never become God’s enemy

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SINCE we are in a Christmas season, l am motivated to put on my preaching cap. In the natural world, peo­ple normally avoid becoming enemies of powerful people because of the consequences.

If people fear to deliberate­ly incur the wrath of influen­tial personalities, it beats my imagination why people would deliberately choose to antago­nise almighty God, the creator of heaven and earth and all the natural things we all see.

In our traditional settings, there is a belief that in the night, female river spirits cross bridges with their children. Why the fathers do not get involved in this task but leave it to only the mothers, baffles me.

Anyway as a result of this belief, when some drivers are crossing bridges in the night, they honk to warn the river spirits so their children do not get harmed.

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Ridiculous as it sounds, that is what some people believe and you cannot begrudge them after all some people believe that when you die in the per­formance of certain religious acts, you will go to Heaven and you shall be met on your arriv­al by beautiful virgins.

Ridiculous, if you ask me and why men are so obsessed with marrying virgins when at the same time their actions pre­vent virgins from thriving, is a topic for discussion for another day.

The Bible says in Deuteron­omy Chapter 4 the verse 24 that “For the Lord thy God is a consuming fire, even a jealous God” KJV. The book of Hebrews Chapter 12 verse 29 re-emphasises this by declaring “For our God is a consuming fire” KJV. This clearly shows us the other side of God’s nature.

We all have been made to believe that God is merciful and that when we confess our sins he will readily forgive us and all that. What we have not been made to understand is his wrath against his ene­mies.

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Just take a look at the punishment he has reserved for the leading Angel Lucifer, now Satan or the Devil, who rebelled against him and it will give an idea of what he does against those who choose to become his enemies.

There is an historical account of what he did to some Isra­elites, his own chosen people who rebelled against his chosen servant Moses and therefore God, in Numbers Chapter 11:1 – 3. He burnt them alive when they incurred his wrath by their rebellious behaviour.

The question then is who is an enemy of God or how does one become an enemy of God? Proverbs give us an indication of how one can become the enemy of God. Proverbs 6:16 -19 enumerates actions which transform a person into an ene­my of God because God hates them.

These include lying, display of pride, character assassina­tion etc. which are rife in our society. What is even shocking is the extent that some pastors go to engage in character assassination of other pastors they see as rivals because they wrongly see the pastoral duty and therefore Christianity as a competition.

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Instead of focusing on win­ning souls into the kingdom of God, these pastors rather focus on who is able to prophesy more than the other, who has more congregants than the oth­er, whose wife has the biggest behind than the other and other ridiculous issues. Once pride sets into a person’s life, he or she becomes an enemy of God.

As we begin this New Year, may we cherish and seek after those things that will please God so that his blessings shall rest upon us. Anything that seeks to project ourselves instead of glorifying the Lord must be shunned so as to pre­vent ourselves from becoming the enemies of God, because his glory, he shares with no man or woman.

Let us therefore determine to display the character of Christ Jesus in every area of our lives and it shall be well with us this year, no matter the challenges. God bless.

By Laud Kissi-Mensah

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International character of Ghanaman and more

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Ghanaians can be found in every part of the world

The average modern Gold Coaster born and bred in Sikaman is an adventurous creature. Go to any part of the world and you’ll find Ghanaman diligently slugging it out either in the snow or in hot sweltering weather, earning a decent living.

Go to Guinea and see Ghanaman in the garb of a herbalist, curing the sick of various ailments. He makes the Guinean understand that not all diseases are caused by James Lucifer alias Jimmy Satan. On the contrary, most diseases are caused by kooko which can even attack the human nose and turn it upside down.

That kooko is also the cause of poverty and the internal bleeding of personal back-pocket economies. And that kooko can be cured using the chemistry underlying Sikaman herbal medicine which has been blessed by the gods of Larteh.

And before Ghanaman starts dispensing his herbal concoctions, he must attract the passing crowd with some Sıkaman-originated choreography, akin to a combination of adowa and agbadza, such that the dancer can easily dislocate a shoulder and start crying for his mother.

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When the crowd is enough to form a quorum, Ghanaman must perform magic as a side-attraction, and proceed to sell his drugs. The drugs are genuinely made from potent herbs which the Pharmacy Board of Sikaman says it has no confidence in. Believe me, Ghanaian herbalists are practising in neighbouring countries like Guinea, Cote d’Ivoire, Sierra Leone and Benin, while we are discouraging them from practising in Sikaman.

Go to Las Palmas and see Ghanaman as a fisherman. He sails on Korean-owned boats and is forced to eat garlic and raw tuna for radiant health. The garlic is also supposed to protect him against witches. But sometimes, he is not good bedfellows with some Korean crew members, and once in a while a fight breaks out.

The typical Korean is a Kung Fu expert and before displaying a golden dragon data. He must first terrify Ghanaman with a Korean dance which consists of wild arms and leg throwing. But Ghanaman is usually not daunted. Why has he been eating cancer kenkey all years without developing cancer? It mean is a superhuman capable of countering Kun fu side-kicks to the ribs.

Anyhow Ghanaman’s most potent arsenal lies in his fists. If he is a southpaw, it mean left fist is probably insured and can cause damage. When Ghanaman lands a cassava blow and it lands on a Korean chest, it has the effect of a cruise missile. If there is no ceasefire a funeral cannot be ruled out.

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Greenland

Go to Alaska and find Ghanaman there. Greenland, Iceland, Brazil, Argentina, Madagascar, everywhere and you’ll find him. He has become an international citizen and is generally lauded for his hardwork, sincerity and honesty.

However, some bad nuts are also condemned and despised.

The world and all its parts and corners are for the human race, and anyone can choose to live anywhere and earn a decent living so long as he doesn’t misconduct himself or become a social misfit and a law unto himself.

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Sıkaman for instance accepts foreigners, and we are so liberal that people just come in through our borders and we welcome them with the best palmwine in town and goat light soup. Who cares about passports and visas? Our hospitality is, as it were legendary.

So we have Liberians, Nigerians, Sierra Leoneans, Togolese, Europeans, Americans, Scandinavians and Koreans in Sikaman.  And some of them have misinterpreted our overzealous accommodation to mean “foolishness” and are misconducting themselves.

The newspapers carry stories of some unscrupulous Nigerians stealing, defrauding and collaborating with their Sikaman counterparts to rob people. You’ll find some good and law-abiding Liberians around but some other Liberians are in the business of fraud, robbery, money printing, money doubling, anything criminal.

Ghanaian hospitality can no longer be extended to such people. I do not think Ghanaians will be treated kindly either, when they misbehave anywhere in the world. Those who come from outside with the intention of bringing down their evil deeds and to practise them here professionally must be getting ready because Ghanaians are getting fed up with the menace.

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These days, you’ll find strange people following you as soon as you emerge from a bank. If you are not careful, they’ll wrestle your briefcase from you and speed away in a waiting taxi.

Someone was just saying that many foreign criminals are flocking to Ghana because in their countries, they are enable to operate either because they are being looked for by the police for offences committed or fear instant justice at the hands of mobs. Ghanaians, it is said, are humanitarian in dealing with criminals.

Well, in some African countries, a thief who is being chased runs directly to the police station in his own interest and begs the officer at the counter to lock him up. Otherwise he’ll be lynched or be burnt to death. In Ghana, it is the opposite. The thieves run far away from the cop stations.

The criminals must reform and stay peacefully in Sikaman or quit. No court case!

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This article was first published on Saturday September 5, 1998

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The architecture of existence: How we live and die

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​The human condition is defined by two absolute, biological bookends: the commencement of complex cellular animation and its ultimate, irreversible cessation.

For centuries, medicine treated life and death as strictly separate states. Today, modern pathology and molecular biology reveal a more profound truth: the mechanisms that allow us to live are the exact same mechanisms that dictate how we die.

​Understanding this relationship is no longer just a philosophical pursuit. It is a clinical necessity for managing public health in the 21st century.

Part I: How we live – The mechanics of animation

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​At its core, biological life is a continuous, high-stakes battle against entropy (the natural tendency of systems to degrade into disorder). To maintain form, consciousness, and function, the human body relies on three fundamental pillars:

1. Cellular respiration and energy production

​Every second of human life is powered by the conversion of oxygen and glucose into Adenosine Triphosphate (ATP), the universal energy currency of our cells. This process occurs within the mitochondria.

Without a constant supply of ATP, the microscopic pumps that maintain electrical gradients across our cell membranes fail, causing cellular collapse within minutes.

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2. Homeostasis: The balancing act

​To survive, the internal environment of the body must remain incredibly stable, regardless of external chaos. This balancing act, known as homeostasis, regulates:

​Blood pH: Strictly maintained between 7.35 and 7.45.

​Core Temperature: Ideally kept around 37°C (98.6°F).

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​Electrolyte Balance: Precise ratios of sodium, potassium, and calcium that allow nerves to fire and muscles to contract.

​3. The Autonomic Nervous System (ANS)

​The ANS acts as the invisible conductor of life, split into two complementary branches:

Part II: How we die – The path of cessation

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​Death is rarely a singular event; it is a progressive biological cascade. Whether caused by old age, chronic illness, or sudden trauma, the final pathways of mortality generally follow a predictable trajectory.

​1. The cellular horizon: Senescence and Apoptosis

​Every time a human cell divides, the protective caps at the ends of its chromosomes-telomeres-shorten. Eventually, telomeres become so depleted that the cell can no longer divide safely. It enters senescence (a state of permanent arrest) or triggers apoptosis (programmed cell death). This gradual, systemic loss of cellular renewal is the underlying engine of aging.

​2. The clinical cascade of somatic death

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​When the body can no longer maintain homeostasis, somatic death (the death of the organism as a whole) begins. This occurs in a distinct sequence:

1

Clinical Death

Zero to four minutes

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The heart stops pumping blood, and respiration ceases. While breathing and circulation have ended, the body’s tissues still contain residual oxygen and cellular energy reserves. At this stage, resuscitation is often still possible.

2

Brain Death (Infarction)

Four to six minutes

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Deprived of fresh oxygenated blood, the brain’s highly sensitive neurons begin to starve. Lacking ATP, the brain cells lose their electrical charge, swell, and begin to burst. Permanent, irreversible neurological damage occurs within minutes.

3

Biological Death

Hours to days

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The organs fail entirely. Without central control or blood flow, individual cells throughout the body consume their final energy reserves. Enzymes that once aided digestion begin to break down the body’s own tissues from the inside out, a process known as autolysis.

Part III: The modern collision of life and death

​In the modern era, the boundary between how we live and how we die has blurred. Historically, humanity died primarily from infectious diseases and acute trauma. Today, global mortality is dominated by non-communicable, chronic lifestyle diseases.

Modern Pathology: How we live (the cause) how we die (the result)

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Cardiovascular disease, chronic stress, poor diet, and lack of sleep keep the sympathetic nervous system hyper-activated, damaging blood vessels .Occlusion of coronary arteries leads to myocardial infarction (heart attack) or ischemic stroke.

Metabolic syndrome over nutrition and physical inactivity overwhelm cellular mitochondria, leading to systemic insulin resistance. Multi-organ failure, chronic kidney disease, and severe vascular complications.

Neurodegenerative Disorders Chronic systemic inflammation and sleep deprivation prevent the brain from clearing metabolic waste. Gradual loss of synaptic connections, leading to dementia and the eventual loss of basic autonomic functions.

Conclusion: The unified theory of health

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​Ultimately, how we live directly shapes the path of how we die. The micro-choices of daily existence-how we manage emotional stress, the quality of our rest, our communal connections, and our nutrition-either preserve the integrity of our homeostatic systems or accelerate their decline.

​True medical advancement is shifting away from merely extending the final, frail stages of biological death. Instead, the focus is turning toward optimising our living years-ensuring that the intricate, beautiful machinery of human animation runs smoothly until its natural, quiet conclusion.

By Robert Ekow Grimmond-Thompson

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