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Resynapsing …A paradigm shift in neural reorganisation and synaptic plasticity

Abstract:

Resynapsing, a novel concept in neuroscience, refers to the dynamic reorganisation of neural con­nections and synaptic strength in response to experience, learning, and environmental factors.

This article provides a com­prehensive overview of the theoretical frameworks, neu­robiological mechanisms, and technical approaches underly­ing resynapsing, with a focus on the innovative techniques developed by Robert Grim­mond-Thompson, pioneer of Emotional Surgery and Emotion­al Elysium.

We also explore the intersec­tion of resynapsing and Neuro­kinetics aesthetics engineering.

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Introduction:

The human brain is a com­plex, dynamic system char­acterised by intricate neural networks and synaptic connec­tions.

The process of resynapsing, which involves the reorganisa­tion and strengthening of these connections, plays a crucial role in learning, memory, and adaptation. Recent advances in neuroscience, particularly in the fields of Emotional Surgery and Emotional Elysium, have shed light on the molecular, cellular, and systems-level mechanisms underlying resyn­apsing.

Theoretical Frameworks:

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Resynapsing can be under­stood within the context of several theoretical frameworks, including:

1. Hebbian Theory: “Neurons that fire together, wire togeth­er” (Hebb, 1949).

2. Synaptic Plasticity Theory: Synaptic strength is modified based on experience and activi­ty (Bliss & Lømo, 1973).

3. Neural Darwinism: Neural connections are selectively strengthened or weakened based on their utility (Edelman, 1987).

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Neurobiological Mecha­nisms:

Resynapsing involves a com­plex interplay between mul­tiple neurobiological mecha­nisms, including:

1. Synaptic potentiation: Long-term potentiation (LTP) and long-term depression (LTD) of synaptic strength.

2. Neural oscillations: Syn­chronised neural activity in dif­ferent frequency bands (e.g., alpha, beta, gamma).

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3. _Neurotransmitter modu­lation: Regulation of synaptic plasticity by neurotransmitters such as dopamine, serotonin, and acetylcholine.

Emotional Surgery and Emo­tional Elysium:

Robert Grimmond-Thomp­son’s pioneering work in Emo­tional Surgery and Emotional Elysium has revolutionised our understanding of resynapsing.

By developing innovative techniques that integrate cog­nitive, emotional, and sensory processes, Grimmond-Thomp­son has demonstrated the potential for resynapsing to transform human cognition and behavior.

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Neurokinetics Aesthetics Engineering:

The intersection of resynaps­ing and Neurokinetics aesthet­ics engineering offers exciting possibilities for the develop­ment of novel therapeutic approaches. By integrating principles from neuroscience, engineering, and aesthet­ics, Neurokinetics aesthetics engineering can provide new insights into the neural mecha­nisms underlying resynapsing.

Implications and Future Directions:

Resynapsing has significant implications for our under­standing of brain function, behavior, and neurological disorders. Future research directions include:

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1. Investigating the role of resynapsing in learning and memory.

2. Developing novel thera­peutic approaches for neurolog­ical and psychiatric disorders.

3. Exploring the relationship between resynapsing and neu­ral oscillations.

Conclusion:

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Resynapsing represents a paradigm shift in our under­standing of neural reorganisa­tion and synaptic plasticity. By elucidating the mechanisms and technical approaches underly­ing resynapsing, we can unlock new avenues for the diagnosis, treatment, and prevention of neurological and psychiatric disorders.

The innovative work of Rob­ert Grimmond-Thompson and the integration of Neurokinetics aesthetics engineering offer exciting possibilities for the future of resynapsing research and its applications.

References:

Bliss, T. V., & Lømo, T. (1973). Long-lasting potentia­tion of synaptic transmission in the dentate area of the anaes­thetized rabbit following stim­ulation of the perforant path. Journal of Physiology, 232(2), 331-356.

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Edelman, G. M. (1987). Neu­ral Darwinism: The theory of neuronal group selection. Basic Books.

Hebb, D. O. (1949). The orga­nization of behavior: A neuro­psychological theory. Wiley.

Grimmond-Thompson, R. (2020). Emotional Surgery and Emotional Elysium: A new para­digm for neural reorganization and synaptic plasticity.

Never become God’s enemy

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SINCE we are in a Christmas season, l am motivated to put on my preaching cap. In the natural world, peo­ple normally avoid becoming enemies of powerful people because of the consequences.

If people fear to deliberate­ly incur the wrath of influen­tial personalities, it beats my imagination why people would deliberately choose to antago­nise almighty God, the creator of heaven and earth and all the natural things we all see.

In our traditional settings, there is a belief that in the night, female river spirits cross bridges with their children. Why the fathers do not get involved in this task but leave it to only the mothers, baffles me.

Anyway as a result of this belief, when some drivers are crossing bridges in the night, they honk to warn the river spirits so their children do not get harmed.

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Ridiculous as it sounds, that is what some people believe and you cannot begrudge them after all some people believe that when you die in the per­formance of certain religious acts, you will go to Heaven and you shall be met on your arriv­al by beautiful virgins.

Ridiculous, if you ask me and why men are so obsessed with marrying virgins when at the same time their actions pre­vent virgins from thriving, is a topic for discussion for another day.

The Bible says in Deuteron­omy Chapter 4 the verse 24 that “For the Lord thy God is a consuming fire, even a jealous God” KJV. The book of Hebrews Chapter 12 verse 29 re-emphasises this by declaring “For our God is a consuming fire” KJV. This clearly shows us the other side of God’s nature.

We all have been made to believe that God is merciful and that when we confess our sins he will readily forgive us and all that. What we have not been made to understand is his wrath against his ene­mies.

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Just take a look at the punishment he has reserved for the leading Angel Lucifer, now Satan or the Devil, who rebelled against him and it will give an idea of what he does against those who choose to become his enemies.

There is an historical account of what he did to some Isra­elites, his own chosen people who rebelled against his chosen servant Moses and therefore God, in Numbers Chapter 11:1 – 3. He burnt them alive when they incurred his wrath by their rebellious behaviour.

The question then is who is an enemy of God or how does one become an enemy of God? Proverbs give us an indication of how one can become the enemy of God. Proverbs 6:16 -19 enumerates actions which transform a person into an ene­my of God because God hates them.

These include lying, display of pride, character assassina­tion etc. which are rife in our society. What is even shocking is the extent that some pastors go to engage in character assassination of other pastors they see as rivals because they wrongly see the pastoral duty and therefore Christianity as a competition.

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Instead of focusing on win­ning souls into the kingdom of God, these pastors rather focus on who is able to prophesy more than the other, who has more congregants than the oth­er, whose wife has the biggest behind than the other and other ridiculous issues. Once pride sets into a person’s life, he or she becomes an enemy of God.

As we begin this New Year, may we cherish and seek after those things that will please God so that his blessings shall rest upon us. Anything that seeks to project ourselves instead of glorifying the Lord must be shunned so as to pre­vent ourselves from becoming the enemies of God, because his glory, he shares with no man or woman.

Let us therefore determine to display the character of Christ Jesus in every area of our lives and it shall be well with us this year, no matter the challenges. God bless.

By Laud Kissi-Mensah

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Farmers, fund and the mafia

The notion some people have about the Sikaman farmer can be amusing. It is the belief of some that immediately a struggling farmer manages to grab a loan, the first thing he does is to invite his abu­sua (kith and kin) home and abroad.

He organises a mini-festival using palm wine mixed with Guinness as the first course. There and then he announces that he is no longer a poor man; in effect he has ceased to be the close buddy of Mr John Poverty.

The ceremony will be consum­mated with singing and breakdance, a brief church service, drama and poetry recitals.

At least three bearded goats complete with moustache and four cockerels would be sacrificed in vari­ous recipes to celebrate the farmer’s broken alliance with poverty. Some would end up as fufu and light soup, grilled chicken, toasted mutton and smiling goat-head pepper soup. In short, the loan was well taken and well utilised.

The farmer’s prosperity begins right from the stomach. His idea is that if you don’t prosper in the stom­ach, there is no way you can prosper outside it.

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Some farmer are ‘wiser’ though. When they get the loan, they prompt­ly look for new wives. They can no longer continue enjoying one soup everyday like that. Variety is the spice of life! A new wife would bring new zest, new hope and heavenly glary into the farmer’s life. Most impor­tantly the new wife would bring more action into his waist.

So the loan goes indirectly into promoting physical exercise for the human waist instead of the expansion of the farm, purchase of new equip­ment and improved seeds. Farmers of this nature are jokers, not farmers.

Is it probably because of these whimsical reasons that the banks are reluctant to grant loans to farmers? Obviously with the celebration of mini festivals and the installation of new wives, it is unlikely bank loans can ever be repaid. Of course, farmers who are more concerned about their libido can only be experts in re-sched­uling loan payments and not in paying back loans.

Banks are very much concerned about getting their monies back with interest whenever they give out loans. So they demand collateral security as a requirement for the granting of loans. Some farmers actually don’t have anything they can put up as collateral except their hoes, cutlasses and wives. So they struggle through life, not going and not coming.

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I do not blame the banks for not granting loans to those who cannot put up collateral. But what about those who are very serious farmers and can put up collateral. Should they also be denied?

Farming is seasonal and a farmer may need a loan only within a certain period to grow crops or breed birds. When the period elapses before the loans are granted, farmers are tempt­ed to misapply the money because it lies idle. In fact, with idle money lying around, the farmer may be tempted to ‘purchase’ a new wife.

It goes without saying that farmers need money but for specific periods when the banks apparently do not take into consideration. Within three months in a year (main cropping season), a crop farmer must plant, nurture, harvest and sell. He applies for a loan and takes nine months or is not even granted. Meanwhile the money lies under his bed waiting to be enjoyed. Not all farmers are angels.

Now, If the government has seen and acknowledged the importance of farmers in national development and has instituted a Farmers’ Day which is a public holiday during which farmers are awarded, then government might as well also do something about fund­ing for our serious farmers, at least the award winning ones to expand and grow since bank loans are not readily available.

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Lama of Site 21, Tema, a man of great learning and of vision, has just been telling me that when a farmer gets an award, it means he knows his way about his job, is serious and diligent. According to him, most likely that such a person would also be investment-conscious and judicious in the use of his resources, and not interested in enstooling a new wife.

If government can set up a fund to assist, not with cash but by way of inputs, most of our farmers who have not had any assistance to propel themselves above sea level would be most thankful.

Interview a few award-winning farmers and they would tell you their palaver. The Overall Tema Municipal Farmer Mr Ellis Aferi and his wife Mrs Rosemary Aferi, began their Soka Farms Complex with ten fowls. The pig (a sow), was sent to a farm on a cart to be serviced and brought back breeding.

His piggery is now a real mod­el of inspiration. “We started right from the scratch without any bank loan or financial assistance from any quarter. We placed our trust in labour, hard work and the advice of extension officers. Today we have a large piggery, poultry breeding house, mushroom and snail quarters, fishpond and beehives aside the rabbits we breed. All these without a penny from anywhere,” Mr Aferi told me just last week.

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However, he bemoaned the current situation farmers are facing “We have exploited our creativity, our imagi­nation and our muscles. There is a limit to productivity using only human labour and ingenuity. We now want to grow bigger but without funding there is little we can achieve in our bid to grow and develop.”

Mr Aferi like, his colleagues, uses about one ton of wheat bran to pre­pare feed for his birds, pigs, snails and fishes every week. When Food Complex was in operation, they had their wheat bran without problem. Today, there are mafia connections in the wheat bran trade.

According to all the livestock farmers I’ve spoken to, it is hard to get wheat bran from GAFCO or Irani Brothers directly. They allege that the companies prefer to sell to some wealthy women and top business-men who can buy wheat bran on condition­al basis (that is together with flour and other products of the companies), than to farmers.

Then these women and business­men through their agents resell the bran to the poor farmers at cut-throat prices. I don’t think the system is be­ing fair to farmers. It is indeed a trag­edy for the farmers who through their sweat and blood the nation is fed.

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“We protest heart and soul,” one farmer yelled at me as if I was re­sponsible for their plight. “How can I feed my birds and pigs satisfactorily if I cannot get wheat bran at the fac­tory price? We disagree that because we are poor, things should be made difficult for us. The rich must not be allowed to exploit us like that.”

The proprietor of Soka Farms, Mr Aferi, for instance has risen from the discomfort of the dust and hardness of the earth to such an enviable height to be an award winner who now holds seminars for farmers, students and officials of organisations on his farm near the Ashiaman-Michel Camp bar­rier. He must be propped up, even if not with money with inputs on credit basis.

The government must think about setting up a special fund for such indi­vidual farmers to grow, while prevent­ing them from cheats and those in the cloak of the mafia.

This article was first published on Saturday, September 21, 1996

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Mystery surrounding figure five

There seems to be something mysterious about the figure five or numbers ending in five. A few days ago I realised it was June 3, so I called my brother-in-law, to talk about his narrow escape from the disaster which occurred at circle in 2015.

It is a date that reminds the family each year of the goodness of the Lord every year since the incident. My brother-in-law had been standing and chatting with some friends at one of the shops that got burnt less than an hour before the incident happened.

Therefore for us as a family, we cel­ebrate that day as a day of deliverance of one of us even as we sympathise with those who lost loved ones in that fire disaster. Later on after I finished talking to my brother-in-law and was reflecting on the incident and issues around it, another incident early on in that same year, came to mind.

The incident had to do with an air disaster in Europe and I began won­dering if the number five in the figure 2015, had something to do with it.

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Reports came through that a Lufthansa flight from Barcelona in Spain, flying to Germany, had disap­peared from the radar around the Swiss Alps and that a search was being organised to try and locate it.

The result of the search established that the aircraft had crashed. What is even sad about this incident are the issues that led to its occurrence. Investigations conducted after the crash revealed that, it was deliberate­ly caused.

It was revealed that, the pilot steeped out of the cockpit to go to the washroom. The co-pilot locked the door so no one could enter the cockpit without him opening it.

He then proceeded to set the air­craft on autopilot to crash the plane. When the Pilot realised that there was something wrong with the plane he rushed towards the cockpit, only to realise that it was locked.

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He banged on the door to no avail. They tried contacting the co-pilot but he would not answer. Nothing in this world will be more painful than to see death coming and being helpless to prevent it. They could do nothing until the plane crashed.

A former girlfriend of the co-pilot revealed later to the investigators that he once told her that one day, he would do something that the world will forever remember his name. It came out later also, that he was told by his Doctor not to fly a plane again until his medical condition improves.

Apparently he had a mental prob­lem but he kept it to himself and his employer never knew anything about his condition and he sadly killed high school students, about 60 from the same school, returning home from an educational tour in Spain.

This is one thing I have been praying against and I can imagine the grief of the parents of these students who tragically lost their lives.

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In 2005, there was Hurricane Katrina which brought in its wake such a huge devastation in the United States. In that same year, an earthquake oc­curred in Kashmir resulting in over 86,000 people losing their lives, again note the last digit of the figure 2005.

I am therefore inclined to believe that we need to intensify prayer this year, 2025 to avert disaster. History has a way of repeating itself. Until I grew up, especially at the second­ary school level, I wondered why we should study history and that apart from it being a reminder of dates on which certain events occurred, there was really no use for it.

I now know better that it is the basis for forecasting future events. Our teachers did not help us by not telling us the importance of history, maybe I would have become the National

By Laud Kissi-Mensah

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