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Resynapsing …A paradigm shift in neural reorganisation and synaptic plasticity

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Abstract:

Resynapsing, a novel concept in neuroscience, refers to the dynamic reorganisation of neural con­nections and synaptic strength in response to experience, learning, and environmental factors.

This article provides a com­prehensive overview of the theoretical frameworks, neu­robiological mechanisms, and technical approaches underly­ing resynapsing, with a focus on the innovative techniques developed by Robert Grim­mond-Thompson, pioneer of Emotional Surgery and Emotion­al Elysium.

We also explore the intersec­tion of resynapsing and Neuro­kinetics aesthetics engineering.

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Introduction:

The human brain is a com­plex, dynamic system char­acterised by intricate neural networks and synaptic connec­tions.

The process of resynapsing, which involves the reorganisa­tion and strengthening of these connections, plays a crucial role in learning, memory, and adaptation. Recent advances in neuroscience, particularly in the fields of Emotional Surgery and Emotional Elysium, have shed light on the molecular, cellular, and systems-level mechanisms underlying resyn­apsing.

Theoretical Frameworks:

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Resynapsing can be under­stood within the context of several theoretical frameworks, including:

1. Hebbian Theory: “Neurons that fire together, wire togeth­er” (Hebb, 1949).

2. Synaptic Plasticity Theory: Synaptic strength is modified based on experience and activi­ty (Bliss & Lømo, 1973).

3. Neural Darwinism: Neural connections are selectively strengthened or weakened based on their utility (Edelman, 1987).

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Neurobiological Mecha­nisms:

Resynapsing involves a com­plex interplay between mul­tiple neurobiological mecha­nisms, including:

1. Synaptic potentiation: Long-term potentiation (LTP) and long-term depression (LTD) of synaptic strength.

2. Neural oscillations: Syn­chronised neural activity in dif­ferent frequency bands (e.g., alpha, beta, gamma).

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3. _Neurotransmitter modu­lation: Regulation of synaptic plasticity by neurotransmitters such as dopamine, serotonin, and acetylcholine.

Emotional Surgery and Emo­tional Elysium:

Robert Grimmond-Thomp­son’s pioneering work in Emo­tional Surgery and Emotional Elysium has revolutionised our understanding of resynapsing.

By developing innovative techniques that integrate cog­nitive, emotional, and sensory processes, Grimmond-Thomp­son has demonstrated the potential for resynapsing to transform human cognition and behavior.

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Neurokinetics Aesthetics Engineering:

The intersection of resynaps­ing and Neurokinetics aesthet­ics engineering offers exciting possibilities for the develop­ment of novel therapeutic approaches. By integrating principles from neuroscience, engineering, and aesthet­ics, Neurokinetics aesthetics engineering can provide new insights into the neural mecha­nisms underlying resynapsing.

Implications and Future Directions:

Resynapsing has significant implications for our under­standing of brain function, behavior, and neurological disorders. Future research directions include:

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1. Investigating the role of resynapsing in learning and memory.

2. Developing novel thera­peutic approaches for neurolog­ical and psychiatric disorders.

3. Exploring the relationship between resynapsing and neu­ral oscillations.

Conclusion:

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Resynapsing represents a paradigm shift in our under­standing of neural reorganisa­tion and synaptic plasticity. By elucidating the mechanisms and technical approaches underly­ing resynapsing, we can unlock new avenues for the diagnosis, treatment, and prevention of neurological and psychiatric disorders.

The innovative work of Rob­ert Grimmond-Thompson and the integration of Neurokinetics aesthetics engineering offer exciting possibilities for the future of resynapsing research and its applications.

References:

Bliss, T. V., & Lømo, T. (1973). Long-lasting potentia­tion of synaptic transmission in the dentate area of the anaes­thetized rabbit following stim­ulation of the perforant path. Journal of Physiology, 232(2), 331-356.

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Edelman, G. M. (1987). Neu­ral Darwinism: The theory of neuronal group selection. Basic Books.

Hebb, D. O. (1949). The orga­nization of behavior: A neuro­psychological theory. Wiley.

Grimmond-Thompson, R. (2020). Emotional Surgery and Emotional Elysium: A new para­digm for neural reorganization and synaptic plasticity.

Never become God’s enemy

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SINCE we are in a Christmas season, l am motivated to put on my preaching cap. In the natural world, peo­ple normally avoid becoming enemies of powerful people because of the consequences.

If people fear to deliberate­ly incur the wrath of influen­tial personalities, it beats my imagination why people would deliberately choose to antago­nise almighty God, the creator of heaven and earth and all the natural things we all see.

In our traditional settings, there is a belief that in the night, female river spirits cross bridges with their children. Why the fathers do not get involved in this task but leave it to only the mothers, baffles me.

Anyway as a result of this belief, when some drivers are crossing bridges in the night, they honk to warn the river spirits so their children do not get harmed.

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Ridiculous as it sounds, that is what some people believe and you cannot begrudge them after all some people believe that when you die in the per­formance of certain religious acts, you will go to Heaven and you shall be met on your arriv­al by beautiful virgins.

Ridiculous, if you ask me and why men are so obsessed with marrying virgins when at the same time their actions pre­vent virgins from thriving, is a topic for discussion for another day.

The Bible says in Deuteron­omy Chapter 4 the verse 24 that “For the Lord thy God is a consuming fire, even a jealous God” KJV. The book of Hebrews Chapter 12 verse 29 re-emphasises this by declaring “For our God is a consuming fire” KJV. This clearly shows us the other side of God’s nature.

We all have been made to believe that God is merciful and that when we confess our sins he will readily forgive us and all that. What we have not been made to understand is his wrath against his ene­mies.

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Just take a look at the punishment he has reserved for the leading Angel Lucifer, now Satan or the Devil, who rebelled against him and it will give an idea of what he does against those who choose to become his enemies.

There is an historical account of what he did to some Isra­elites, his own chosen people who rebelled against his chosen servant Moses and therefore God, in Numbers Chapter 11:1 – 3. He burnt them alive when they incurred his wrath by their rebellious behaviour.

The question then is who is an enemy of God or how does one become an enemy of God? Proverbs give us an indication of how one can become the enemy of God. Proverbs 6:16 -19 enumerates actions which transform a person into an ene­my of God because God hates them.

These include lying, display of pride, character assassina­tion etc. which are rife in our society. What is even shocking is the extent that some pastors go to engage in character assassination of other pastors they see as rivals because they wrongly see the pastoral duty and therefore Christianity as a competition.

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Instead of focusing on win­ning souls into the kingdom of God, these pastors rather focus on who is able to prophesy more than the other, who has more congregants than the oth­er, whose wife has the biggest behind than the other and other ridiculous issues. Once pride sets into a person’s life, he or she becomes an enemy of God.

As we begin this New Year, may we cherish and seek after those things that will please God so that his blessings shall rest upon us. Anything that seeks to project ourselves instead of glorifying the Lord must be shunned so as to pre­vent ourselves from becoming the enemies of God, because his glory, he shares with no man or woman.

Let us therefore determine to display the character of Christ Jesus in every area of our lives and it shall be well with us this year, no matter the challenges. God bless.

By Laud Kissi-Mensah

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Female bodies for sale

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A man and a woman walking together

It is still the contention of my uncle, Kofi Jogolo, that the moment God created woman, He created a big problem for man. If not, why would man always have to trim his moustache in such a way as to please woman and not himself? And why would a man’s holy organ keep nodding like an agama lizard just because there is a creation called woman?

Sikaman Palava
Sikaman Palava

Sir Kofi Jogolo whose moustache deserves both a national award and mention in the Guinness Book of Records for its stylish variations, told me recently that when you marry, you have palaver; if you don’t marry, you have wahala. All because of woman. I think the bloke is a reincarnation of Paul. Only he looks like Peter.

For those who do not marry, they may be free of marital problems, but might be in sexual bondage, because at dawn, a certain part of the body might nod in distress. It is a wonderful part of the human body that smiles with joy when a woman is lying within arm’s length.

The unmarried may not have to wait until dawn, though. After all, who says you can satisfy a sexual need only at dawn? If there is no girlfriend, there is still a way out. FEMALE BODIES FOR SALE! You only have to ask, “How much?” Sometimes it is worth the price of only two balls of kenkey.

It is for this reason that some people do not discourage women from practising prostitution because they claim the women play a vital role in national development. According to them, first, the nation cannot develop when the citizens are sex-starved. Second, they claim prostitution keeps down figures of rape cases since it is due to the scarcity of female bodies that the incidence of rape is rising.

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Well, some people really adore prostitutes. With them you don’t have to worry about pregnancy. Moreover, you can skip foreplay which many people don’t have the patience for because of their high sexual temperature, or because they consider it a waste of time. And when you pay well, you can enjoy the style you want.

In actual fact, some married men also go in for prostitutes once in a while. They claim that prostitutes do not complain in bed like their wives. When you ask them to raise a leg, they comply without argument.

They also say prostitutes who are experienced can really work on certain parts of your body enough to make you blaspheme. Holy Jesus! The difference is clear then that with prostitutes you pay for the service but with wives it is for free, meaning that the quality of service must differ accordingly.

Many men also say they prefer prostitutes to girlfriends because of “back-pocket palaver”. It is their contention that with girlfriends you have to specialise in telling lies about your credit worthiness especially when you’re not only a human being but also a church mouse.

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Sometimes you have to buy beer and gin because some girlfriends would not like to have sex unless they are properly soaked in booze. You also have to sing them lullabies and recite poetry to turn them on. Ask Devine Ankamah. That’s not all. When all is finished, you have to dish transport money, and if you’re not lucky she’d ask you to settle a “carry forward” you had planned to dodge.

So for just two probably lousy rounds of enjoyment, you’d spend some ¢15,000 if hotel services are included, unless you choose a hotel room where cockroaches and rats don’t practise family planning.

There are those who believe that with prostitutes, you don’t have to tell lies. It is purely business. No credit, no debit. Money na hand back na ground. When you are through and refuse to pay, she’ll cause a scene, scratch your face red and drag your butt onto the street. Next time you don’t have money, you stick to your wife or girlfriend or to your sorrows.

Prostitution in Sikaman is widespread. News reaching Palava have it that in the Obuasi area, it is the major occupation of females. They are in lucrative business. They come from all over the country -Bolga, Tamale, Kumasi, Sunyani, Accra, Odumase, wherever. A few are said to have come from Lagos in full gear.

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When they all come, they sometimes don’t do so with only their bodies and luggage. They also carry with them something small in the form of a disease called AIDS which they distribute free of charge.

So why Obuasi? Gold! The great successes of Ashanti Goldfields combined with the notoriety and boom of galamsey activities have acted as a magnet, drawing in those who peddle their bodies for cash. No cheques!

Sometime back, it was reported that AIDS cases in the Obuasi area had soared. The reason, prostitution. Obuasi prostitutes are, however, of class. They dress to kill. Some speak even more languages, so if you’re a client and you speak even in tongues, they understand. And they drink beer exactly like Germans.

So what really are we doing about these prostitutes who, some say are contributing to national development and others say are enhancing national obituary?

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Sikaman Palava has said it once that the law enforcement agencies have tried time and again to rid them off the streets. They have always failed in doing so. The problem is that they are as slippery as the cockroach. When harassed, they disappear and practise all the same. If caught, they are fined and the next day they are firmly at post.

Some people say because we can’t get rid of them, we must neither encourage nor discourage them. We must find a way of organising them into co-operatives under the name of “SPECIAL HUMAN SERVICES.”

They’d undergo medical screening and those with AIDS banned from practising. The rest would undergo a course in the cause, prevention and cure of sexually-transmitted diseases, personal hygiene, condom use and the healthful ways of practising prostitution.

Then they can be let loose to practise under laid-down rules and regulations and their income taxed.

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That way, the prostitutes would be more beneficial to society and would not be the problem we see them to be.

 This article was first published on Saturday June 29, 1996

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The right mindset is everything

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This year June and part of July, is an enjoyable season for football lovers due to the World Cup which is held every four years.  The World Cup is such a huge event and also very prestigious so it is highly competitive. 

Countries registered with the Federation of International Football Association, (FIFA) become automatic members.  FIFA organises tournaments on the five continents of the world, to enable countries to be selected to play in the World Cup competition. 

Governments support their national teams to ensure qualification to the World Cup due to the prestigious nature of the tournament.  Certain countries even go to the extent of renting a place of their choice, instead of the accommodation provided by FIFA, to ensure that they win the ultimate crown, as Germany did in the 2014 tournament in Brazil. 

Mental strength a requisite for emerging victorious in football matches at such high professional level and everything must be done to endure that players are focused on the matches ahead of them.

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There is however, a peculiar situation in this year’s World Cup, where it is being hosted by three countries namely the United States of America, Mexico and Canada and where one of the host countries, is at war with one of the competing countries. 

The United States of America, is waging a war against Iran.  The US has prevented Iran from staying in the US where they were originally scheduled by FIFA to play their matches.  The US using its power as the host country, has refused to let Iran to stay and FIFA has provided a place in Mexico for the Iranian team to stay.  They have to spend about five hours to fly to the US and prepare to get ready for their matches, each match day. 

They are also forced to leave the US as soon as they finish playing their matches, without resting.  Despite this inhumane treatment being forced on them by the USA, the Iranian team is mentally strong and have managed to draw their two matches played.  

This is a clear manifestation of mental toughness, resulting from having the right mindset.

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Life has a way of often dealing bad cards to a lot of people but it is important that when it happens like that, you look at what you can do with what you have, to still achieve the goals you have set for yourself.

 There is a saying that when life throws you a lemon you make lemonade out of it.  The barriers confronting you might be great, but it is the attitude you display that makes the difference. 

The Iranians have really shown that the right mindset is indeed everything you need to be successful.  They looked at their situation and assessed what was not going in their favour and found appropriate steps to address it. 

Given the teams Iran was to play, the challenge was indeed huge, given the circumstances they found themselves in, but the right mindset to never give up, did the trick for them.

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As human beings, we are always confronted with challenges, right from the day we start to crawl, the day we take our first steps and as we continue to grow into adulthood.  Challenges are part of our daily lives and we must therefore condition our minds, that we shall encounter them and so must constantly be innovative in overcoming them, when we encounter them. 

We need as a country, to develop a critical thinking skill capabilities in our youth, as an investment in the future fortunes of this country.  Developing the right mindset, will enable us overcome every challenge.  God bless.

By Laud Kissi-Mensah

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