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Resynapsing …A paradigm shift in neural reorganisation and synaptic plasticity

Abstract:

Resynapsing, a novel concept in neuroscience, refers to the dynamic reorganisation of neural con­nections and synaptic strength in response to experience, learning, and environmental factors.

This article provides a com­prehensive overview of the theoretical frameworks, neu­robiological mechanisms, and technical approaches underly­ing resynapsing, with a focus on the innovative techniques developed by Robert Grim­mond-Thompson, pioneer of Emotional Surgery and Emotion­al Elysium.

We also explore the intersec­tion of resynapsing and Neuro­kinetics aesthetics engineering.

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Introduction:

The human brain is a com­plex, dynamic system char­acterised by intricate neural networks and synaptic connec­tions.

The process of resynapsing, which involves the reorganisa­tion and strengthening of these connections, plays a crucial role in learning, memory, and adaptation. Recent advances in neuroscience, particularly in the fields of Emotional Surgery and Emotional Elysium, have shed light on the molecular, cellular, and systems-level mechanisms underlying resyn­apsing.

Theoretical Frameworks:

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Resynapsing can be under­stood within the context of several theoretical frameworks, including:

1. Hebbian Theory: “Neurons that fire together, wire togeth­er” (Hebb, 1949).

2. Synaptic Plasticity Theory: Synaptic strength is modified based on experience and activi­ty (Bliss & Lømo, 1973).

3. Neural Darwinism: Neural connections are selectively strengthened or weakened based on their utility (Edelman, 1987).

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Neurobiological Mecha­nisms:

Resynapsing involves a com­plex interplay between mul­tiple neurobiological mecha­nisms, including:

1. Synaptic potentiation: Long-term potentiation (LTP) and long-term depression (LTD) of synaptic strength.

2. Neural oscillations: Syn­chronised neural activity in dif­ferent frequency bands (e.g., alpha, beta, gamma).

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3. _Neurotransmitter modu­lation: Regulation of synaptic plasticity by neurotransmitters such as dopamine, serotonin, and acetylcholine.

Emotional Surgery and Emo­tional Elysium:

Robert Grimmond-Thomp­son’s pioneering work in Emo­tional Surgery and Emotional Elysium has revolutionised our understanding of resynapsing.

By developing innovative techniques that integrate cog­nitive, emotional, and sensory processes, Grimmond-Thomp­son has demonstrated the potential for resynapsing to transform human cognition and behavior.

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Neurokinetics Aesthetics Engineering:

The intersection of resynaps­ing and Neurokinetics aesthet­ics engineering offers exciting possibilities for the develop­ment of novel therapeutic approaches. By integrating principles from neuroscience, engineering, and aesthet­ics, Neurokinetics aesthetics engineering can provide new insights into the neural mecha­nisms underlying resynapsing.

Implications and Future Directions:

Resynapsing has significant implications for our under­standing of brain function, behavior, and neurological disorders. Future research directions include:

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1. Investigating the role of resynapsing in learning and memory.

2. Developing novel thera­peutic approaches for neurolog­ical and psychiatric disorders.

3. Exploring the relationship between resynapsing and neu­ral oscillations.

Conclusion:

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Resynapsing represents a paradigm shift in our under­standing of neural reorganisa­tion and synaptic plasticity. By elucidating the mechanisms and technical approaches underly­ing resynapsing, we can unlock new avenues for the diagnosis, treatment, and prevention of neurological and psychiatric disorders.

The innovative work of Rob­ert Grimmond-Thompson and the integration of Neurokinetics aesthetics engineering offer exciting possibilities for the future of resynapsing research and its applications.

References:

Bliss, T. V., & Lømo, T. (1973). Long-lasting potentia­tion of synaptic transmission in the dentate area of the anaes­thetized rabbit following stim­ulation of the perforant path. Journal of Physiology, 232(2), 331-356.

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Edelman, G. M. (1987). Neu­ral Darwinism: The theory of neuronal group selection. Basic Books.

Hebb, D. O. (1949). The orga­nization of behavior: A neuro­psychological theory. Wiley.

Grimmond-Thompson, R. (2020). Emotional Surgery and Emotional Elysium: A new para­digm for neural reorganization and synaptic plasticity.

Never become God’s enemy

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SINCE we are in a Christmas season, l am motivated to put on my preaching cap. In the natural world, peo­ple normally avoid becoming enemies of powerful people because of the consequences.

If people fear to deliberate­ly incur the wrath of influen­tial personalities, it beats my imagination why people would deliberately choose to antago­nise almighty God, the creator of heaven and earth and all the natural things we all see.

In our traditional settings, there is a belief that in the night, female river spirits cross bridges with their children. Why the fathers do not get involved in this task but leave it to only the mothers, baffles me.

Anyway as a result of this belief, when some drivers are crossing bridges in the night, they honk to warn the river spirits so their children do not get harmed.

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Ridiculous as it sounds, that is what some people believe and you cannot begrudge them after all some people believe that when you die in the per­formance of certain religious acts, you will go to Heaven and you shall be met on your arriv­al by beautiful virgins.

Ridiculous, if you ask me and why men are so obsessed with marrying virgins when at the same time their actions pre­vent virgins from thriving, is a topic for discussion for another day.

The Bible says in Deuteron­omy Chapter 4 the verse 24 that “For the Lord thy God is a consuming fire, even a jealous God” KJV. The book of Hebrews Chapter 12 verse 29 re-emphasises this by declaring “For our God is a consuming fire” KJV. This clearly shows us the other side of God’s nature.

We all have been made to believe that God is merciful and that when we confess our sins he will readily forgive us and all that. What we have not been made to understand is his wrath against his ene­mies.

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Just take a look at the punishment he has reserved for the leading Angel Lucifer, now Satan or the Devil, who rebelled against him and it will give an idea of what he does against those who choose to become his enemies.

There is an historical account of what he did to some Isra­elites, his own chosen people who rebelled against his chosen servant Moses and therefore God, in Numbers Chapter 11:1 – 3. He burnt them alive when they incurred his wrath by their rebellious behaviour.

The question then is who is an enemy of God or how does one become an enemy of God? Proverbs give us an indication of how one can become the enemy of God. Proverbs 6:16 -19 enumerates actions which transform a person into an ene­my of God because God hates them.

These include lying, display of pride, character assassina­tion etc. which are rife in our society. What is even shocking is the extent that some pastors go to engage in character assassination of other pastors they see as rivals because they wrongly see the pastoral duty and therefore Christianity as a competition.

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Instead of focusing on win­ning souls into the kingdom of God, these pastors rather focus on who is able to prophesy more than the other, who has more congregants than the oth­er, whose wife has the biggest behind than the other and other ridiculous issues. Once pride sets into a person’s life, he or she becomes an enemy of God.

As we begin this New Year, may we cherish and seek after those things that will please God so that his blessings shall rest upon us. Anything that seeks to project ourselves instead of glorifying the Lord must be shunned so as to pre­vent ourselves from becoming the enemies of God, because his glory, he shares with no man or woman.

Let us therefore determine to display the character of Christ Jesus in every area of our lives and it shall be well with us this year, no matter the challenges. God bless.

By Laud Kissi-Mensah

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Correcting some doctrinal misconceptions

 This  week I have a very strong desire to talk about the things of God and therefore the Bible. There are a whole lot of misinter­pretation going about in the world as far as the Bible, which is the Word of God, is concerned.

One of the easiest jobs that does not require a licence to get into, is the Pastoral vocation. In this country all you need is a loud voice and even if you do not have, you can seek the aid of a loudspeaker to preach.

Again, one does not have to sit for any exams and all you need to do is to talk to Headmaster of one of the numerous JHS, get a classroom, get a couple of young ladies who have melodious voices and you are good to go.

As a result, we have all manner of people with very questionable characters parading about as Pastors, a.k.a., Men of God. Again, because titles are not something we purchase, they pick all manner of titles after getting a few congregation and trans­ferring the church from a classroom to a structure of their own.

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Suddenly they become Bishop after initial title of Prophet and as some­one said they butcher the scriptures like nobody’s business. We have an interesting country.

One of the misconceptions is the question of whether the Bible endors­es the consumption of Alcohol or not. In the Old Testament which is basi­cally a manual for the relationship between God and his people, Israel, drinking of alcoholic beverages was not forbidden.

However, there was a particular group of people, who were forbidden to consume alcoholic beverages. In Leviticus 10:9-10, God specifically gave a decree for the High Priesthood Order to follow that is, they were to abstain from alcohol throughout the generations.

When we come to the New Testa­ment, the Bible makes it clear to us that, every believer is regarded as a High Priest and therefore a member of the High Priesthood order who are to abstain from strong drink, i.e. alcoholic drink.

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A careful study of the Bible, leads one to conclude that Christians are to shun alcoholic drink because our bod­ies now houses the Spirit of God just like the Tabernacle in Old Testament so we should not contaminate it with unholy things.

There is another issue that raises a lot of argument in Christian circles. The issue of Tithe is a very topical issue that is gainng attention in this era if social media.

Some Christians believe that Tithe is an Old Testament thing and there­fore should not be countenanced in the New Testament era.

To really understand what Tithe is, we need to go to Genesis 14:20 where Tithe originated. It was a sacrifice initiated by Patriarch Abra­ham that was motivated by the Spirit of God after God had given him a mighty victory in battle.

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It therefore became a practice among the descendants of Abraham. God endorsed its observance after the Commandments were given to Moses and was among other reasons to serve as a means for taking care of the needs of the Levites the Priests.

In Malachi God instituted it as an ordinance for generations to come cautioning noncompliance and spec­ifying blessings that will follow its observance. In the New Testament, it was mainly practised as an offering on a weekly basis by the early church and it was received by the leaders, every first day of the week according to 1 Corinthians 16:2.

I intend to periodically attempt to address certain issues that appear controversial in the Bible gradually, we shall have a clearer understand­ing to enrich our knowledge of the Bible.

NB: ‘CHANGE KOTOKA INTERNA­TIONAL AIRPORT TO KOFI BAAKO INTERNATIONAL AIRPORT’

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By Laud Kissi-Mensah

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Monsieur’s daughter —(Part 4)

Sarah and her two younger brothers attended Research School Complex, a fine school run by the research institutions in the Eastern Region. A brilliant child, she enjoyed school, and was always around the top of her class.

She loved her parents. Her mother made sure they lacked nothing. Her father was the easy going type. He was generally good to them, but he hardly spent much time at home. Her major problem was her parents’ continuous quarrels.

During those sessions, the children would recoil in front of the TV in their room till they fell asleep. Very often, they would wake up to hear them quarrelling. Up till she reached junior high, she and her siblings managed to live with the situation. But later on she would hear them exchange threats and insults which confused and scared her.

‘You are a useless man. You are lazy and incompetent at work. Your boss says he’s tired of complaining. He says if you don’t change you could lose your job’.

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‘And you are a heartless and selfish woman. You only care about money and yourself. Why should you go and discuss me with my boss? ‘

‘You dare call me heartless and selfish, when I feed and clothe you and your children? You lazy man. Can you survive for a month if I don’t feed you? When was the last time you took care of any of your children’s expenses, school fees, food, clothing or books?’

‘At the very least I provided you with a home and respectability. Without me you would be living in shame. You would have been ex­posed for who you really are’.

‘If you dare repeat that brainless sentence, I will teach you a lesson you would never forget’.

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‘There you go. Threats! Threats! Why are you always threatening me?’

‘I asked you to repeat that stu­pid statement once, and see what happens’.

‘Okay. I’m sorry. Look, this is not good for the kids. I’m going to town. Will be right back’. With that he dashed out of the door, into his car and noisily sped off.

Although Sarah usually excelled in academics, the turmoil at home was having an impact on her. The teach­ers noticed that she was withdrawn, and would sometimes break into tears with little or no provocation.

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Ms Odame, an elderly English teacher, took an interest in her and, after Sarah had told her about the problems she was facing at home, spent any free time she got encour­aging her. She realised that there was a deep seated problem behind the symptoms she was displaying. One morning, she took her out for lunch, and asked her the hard ques­tion.

‘Sarah, for some time now, I’ve been trying to encourage you, be­cause you are a brilliant girl, even though you may be facing a few problems at home. Now Sarah, I want to do my best to help you, but I want you to try and tell me ex­actly what the problem is at home, and I will do my best to help you. I promise you that I won’t discuss this with your parents’. Without much hesitation she unburdened herself of the load she had been carrying.

‘My parents are always quarrel­ling. Most of the time it is about money. Mummy keeps saying that Daddy doesn’t give her money, but spends his money on going out with friends and girls.

She also says that he is not serious with his work, so he’s not gaining any promotion. But Daddy sometimes says something which infuriates Mummy. He says he has kept her secret and given her respect, so she should stop disturbing her.

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Mummy would then say that the whole issue was Daddy’s making, that if she mentioned it again she would move us out and leave him destitute. He would usually get scared, and apologised. There would be peace for some time, then it would happen again’.

‘I see. I see. Now, Sarah, I want you to trust me on this. I will do my best to help you. Do your best not to dwell on this. Come to me whenever you need any help, but we will solve the problem very soon’.

Through her enquiries, she learnt that Madam Gladys Ababio taught for a while at Aboso Senior High School. She made further enquiries at the GES, and learnt that the current headmaster of the school had been teaching there for close to twenty years. She called him and booked an appointment, explaining that she wanted to make an enquiry about an issue that would help a student of hers who was currently troubled.

‘Thanks for agreeing to see me’, she said after she had been welcomed with a snack. ‘I will go straight to the point. I have a student in JHS three, a girl. She’s brilliant, but she’s troubled at home. She confided in me that her parents have been quarrelling continually, and they seem to be hiding a secret. The mother was a catering teacher here in this school’.

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‘I believe I have your assurance that you will handle this informa­tion with care, since it concerns a minor’.

‘You have my fullest assurance, madam

‘.

‘You are talking about Gladys and David, who were my colleagues. I know them, very well. They separat­ed soon after marrying, and Gladys married one Simon. David was a very popular French teacher. In fact, the school’s playground is named after him.

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He left for Germany as soon as the marriage broke down. He’s back, do­ing big business. He has been doing a lot for the school, but he prefers not to be given any publicity.

Now, let me come to the main issue that has brought you here from Koforidua. Not long after David had married Gladys and was living with her, Simon appeared from America, and spent some time in a hotel with her.

This happened again some months later. David got wind of this, and decided to end the marriage and leave town. Gladys and her relatives begged and begged, but he wouldn’t budge. Then, obviously with the intent of punishing him for rejecting her, Gladys came out and told Mon­sieur that the baby, Sarah, was not his. Indeed, she had told him that she would teach him a lesson.

David was shattered, but his par­ents advised him not to fight Gladys over the issue, because she was quite strong-headed. They told him that the child would come back to him eventually, if she was truly his. So he left town. And Simon married Gladys.

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‘I see. So Sarah is not Simon’s child’.

‘No way. Listen, Sarah was con­ceived before Simon appeared from nowhere. This was known to every­one at Aboso, because David was very popular, a great guy. I don’t know how Gladys can live with her­self, after what she did’.

‘I don’t know how to thank you. I will go back and do my best for the child, without causing much trou­ble’.

By Ekow de Heer

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