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Resynapsing …A paradigm shift in neural reorganisation and synaptic plasticity

Abstract:

Resynapsing, a novel concept in neuroscience, refers to the dynamic reorganisation of neural con­nections and synaptic strength in response to experience, learning, and environmental factors.

This article provides a com­prehensive overview of the theoretical frameworks, neu­robiological mechanisms, and technical approaches underly­ing resynapsing, with a focus on the innovative techniques developed by Robert Grim­mond-Thompson, pioneer of Emotional Surgery and Emotion­al Elysium.

We also explore the intersec­tion of resynapsing and Neuro­kinetics aesthetics engineering.

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Introduction:

The human brain is a com­plex, dynamic system char­acterised by intricate neural networks and synaptic connec­tions.

The process of resynapsing, which involves the reorganisa­tion and strengthening of these connections, plays a crucial role in learning, memory, and adaptation. Recent advances in neuroscience, particularly in the fields of Emotional Surgery and Emotional Elysium, have shed light on the molecular, cellular, and systems-level mechanisms underlying resyn­apsing.

Theoretical Frameworks:

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Resynapsing can be under­stood within the context of several theoretical frameworks, including:

1. Hebbian Theory: “Neurons that fire together, wire togeth­er” (Hebb, 1949).

2. Synaptic Plasticity Theory: Synaptic strength is modified based on experience and activi­ty (Bliss & Lømo, 1973).

3. Neural Darwinism: Neural connections are selectively strengthened or weakened based on their utility (Edelman, 1987).

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Neurobiological Mecha­nisms:

Resynapsing involves a com­plex interplay between mul­tiple neurobiological mecha­nisms, including:

1. Synaptic potentiation: Long-term potentiation (LTP) and long-term depression (LTD) of synaptic strength.

2. Neural oscillations: Syn­chronised neural activity in dif­ferent frequency bands (e.g., alpha, beta, gamma).

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3. _Neurotransmitter modu­lation: Regulation of synaptic plasticity by neurotransmitters such as dopamine, serotonin, and acetylcholine.

Emotional Surgery and Emo­tional Elysium:

Robert Grimmond-Thomp­son’s pioneering work in Emo­tional Surgery and Emotional Elysium has revolutionised our understanding of resynapsing.

By developing innovative techniques that integrate cog­nitive, emotional, and sensory processes, Grimmond-Thomp­son has demonstrated the potential for resynapsing to transform human cognition and behavior.

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Neurokinetics Aesthetics Engineering:

The intersection of resynaps­ing and Neurokinetics aesthet­ics engineering offers exciting possibilities for the develop­ment of novel therapeutic approaches. By integrating principles from neuroscience, engineering, and aesthet­ics, Neurokinetics aesthetics engineering can provide new insights into the neural mecha­nisms underlying resynapsing.

Implications and Future Directions:

Resynapsing has significant implications for our under­standing of brain function, behavior, and neurological disorders. Future research directions include:

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1. Investigating the role of resynapsing in learning and memory.

2. Developing novel thera­peutic approaches for neurolog­ical and psychiatric disorders.

3. Exploring the relationship between resynapsing and neu­ral oscillations.

Conclusion:

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Resynapsing represents a paradigm shift in our under­standing of neural reorganisa­tion and synaptic plasticity. By elucidating the mechanisms and technical approaches underly­ing resynapsing, we can unlock new avenues for the diagnosis, treatment, and prevention of neurological and psychiatric disorders.

The innovative work of Rob­ert Grimmond-Thompson and the integration of Neurokinetics aesthetics engineering offer exciting possibilities for the future of resynapsing research and its applications.

References:

Bliss, T. V., & Lømo, T. (1973). Long-lasting potentia­tion of synaptic transmission in the dentate area of the anaes­thetized rabbit following stim­ulation of the perforant path. Journal of Physiology, 232(2), 331-356.

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Edelman, G. M. (1987). Neu­ral Darwinism: The theory of neuronal group selection. Basic Books.

Hebb, D. O. (1949). The orga­nization of behavior: A neuro­psychological theory. Wiley.

Grimmond-Thompson, R. (2020). Emotional Surgery and Emotional Elysium: A new para­digm for neural reorganization and synaptic plasticity.

Never become God’s enemy

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SINCE we are in a Christmas season, l am motivated to put on my preaching cap. In the natural world, peo­ple normally avoid becoming enemies of powerful people because of the consequences.

If people fear to deliberate­ly incur the wrath of influen­tial personalities, it beats my imagination why people would deliberately choose to antago­nise almighty God, the creator of heaven and earth and all the natural things we all see.

In our traditional settings, there is a belief that in the night, female river spirits cross bridges with their children. Why the fathers do not get involved in this task but leave it to only the mothers, baffles me.

Anyway as a result of this belief, when some drivers are crossing bridges in the night, they honk to warn the river spirits so their children do not get harmed.

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Ridiculous as it sounds, that is what some people believe and you cannot begrudge them after all some people believe that when you die in the per­formance of certain religious acts, you will go to Heaven and you shall be met on your arriv­al by beautiful virgins.

Ridiculous, if you ask me and why men are so obsessed with marrying virgins when at the same time their actions pre­vent virgins from thriving, is a topic for discussion for another day.

The Bible says in Deuteron­omy Chapter 4 the verse 24 that “For the Lord thy God is a consuming fire, even a jealous God” KJV. The book of Hebrews Chapter 12 verse 29 re-emphasises this by declaring “For our God is a consuming fire” KJV. This clearly shows us the other side of God’s nature.

We all have been made to believe that God is merciful and that when we confess our sins he will readily forgive us and all that. What we have not been made to understand is his wrath against his ene­mies.

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Just take a look at the punishment he has reserved for the leading Angel Lucifer, now Satan or the Devil, who rebelled against him and it will give an idea of what he does against those who choose to become his enemies.

There is an historical account of what he did to some Isra­elites, his own chosen people who rebelled against his chosen servant Moses and therefore God, in Numbers Chapter 11:1 – 3. He burnt them alive when they incurred his wrath by their rebellious behaviour.

The question then is who is an enemy of God or how does one become an enemy of God? Proverbs give us an indication of how one can become the enemy of God. Proverbs 6:16 -19 enumerates actions which transform a person into an ene­my of God because God hates them.

These include lying, display of pride, character assassina­tion etc. which are rife in our society. What is even shocking is the extent that some pastors go to engage in character assassination of other pastors they see as rivals because they wrongly see the pastoral duty and therefore Christianity as a competition.

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Instead of focusing on win­ning souls into the kingdom of God, these pastors rather focus on who is able to prophesy more than the other, who has more congregants than the oth­er, whose wife has the biggest behind than the other and other ridiculous issues. Once pride sets into a person’s life, he or she becomes an enemy of God.

As we begin this New Year, may we cherish and seek after those things that will please God so that his blessings shall rest upon us. Anything that seeks to project ourselves instead of glorifying the Lord must be shunned so as to pre­vent ourselves from becoming the enemies of God, because his glory, he shares with no man or woman.

Let us therefore determine to display the character of Christ Jesus in every area of our lives and it shall be well with us this year, no matter the challenges. God bless.

By Laud Kissi-Mensah

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Tears of Ghanaman, home and abroad

• Sikaman residents are more hospital to foreign guests than their own kin
• Sikaman residents are more hospital to foreign guests than their own kin

The typical native of Sikaman is by nature a hospitable creature, a social animal with a big heart, a soul full of the milk of earthly good­ness, and a spirit too loving for its own comfort.

Sikaman Palava
Sikaman Palava

Ghanaman hosts a foreign pal and he spends a fortune to make him very happy and comfortable-good food, clean booze, excellent accommoda­tion and a woman for the night.

Sometimes the pal leaves without saying a “thank you but Ghanaman is not offended. He’d host another idiot even more splendidly. His nature is warm, his spirit benevolent. That is the typical Ghanaian and no wonder that many African-Americans say, “If you haven’t visited Ghana. Then you’ve not come to Africa.

You can even enter the country without a passport and a visa and you’ll be welcomed with a pot of palm wine.

If Ghanaman wants to go abroad, especially to an European country or the United States, it is often after an ordeal.

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He has to doze in a queue at dawn at the embassy for days and if he is lucky to get through to being inter­viewed, he is confronted by someone who claims he or she has the power of discerning truth from lie.

In short Ghanaman must undergo a lie-detector test and has to answer questions that are either nonsensical or have no relevance to the trip at hand. When Joseph Kwame Korkorti wanted a visa to an European country, the attache studied Korkorti’s nose for a while and pronounced judgment.

“The way I see you, you won’t return to Ghana if I allow you to go. Korkorti nearly dislocated her jaw; Kwasiasem akwaakwa. In any case what had Korkorti’s nose got to do with the trip?

If Ghanaman, after several at­tempts, manages to get the visa and lands in the whiteman’s land, he is seen as another monkey uptown, a new arrival of a degenerate ape coming to invade civilized society. He is sneered at, mocked at and avoided like a plague. Some landlords abroad will not hire their rooms to blacks because they feel their presence in itself is bad business.

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When a Sikaman publisher land­ed overseas and was riding in a public bus, an urchin who had the impudence and notoriety of a dead cockroach told his colleagues he was sure the black man had a tail which he was hiding in his pair of trousers. He didn’t end there. He said he was in fact going to pull out the tail for everyone to see.

True to his word he went and put his hand into the backside of the bewildered publisher, intent on grab­bing his imaginary tail and pulling it out. It took a lot of patience on the part of the publisher to avert murder. He practically pinned the white mis­creant on the floor by the neck and only let go when others intervene. Next time too…

The way we treat our foreign guests in comparison with the way they treat us is polar contrasting-two disparate extremes, one totally in­comparable to the other. They hound us for immigration papers, deport us for overstaying and skinheads either target homes to perpetrate mayhem or attack black immigrants to gratify their racial madness

When these same people come here we accept them even more hospi­tably than our own kin. They enter without visas, overstay, impregnate our women and run away.

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About half of foreigners in this country do not have valid resident permits and was not a bother until recently when fire was put under the buttocks of the Immigration Service

In fact, until recently I never knew Sikaman had an Immigration Service. The problem is that although their staff look resplendent in their green outfit, you never really see them any­where. You’d think they are hidden from the public eye.

The first time I saw a group of them walking somewhere, I nearly mistook them for some sixth-form going to the library. Their ladies are pretty though.

So after all, Sikaman has an Immi­gration Service which I hear is now alert 24 hours a day tracking down illegal aliens and making sure they bound the exit via Kotoka Interna­tional. A pat on their shoulder.

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I am glad the Interior Ministry has also realised that the country has been too slack about who goes out or comes into Sikaman.

Now the Ministry has warned foreigners not to take the country’s commitment to its obligations under the various conditions as a sign of weakness or a source for the abuse of her hospitality.

“Ghana will not tolerate any such abuse,” Nii Okaija Adamafio, the Interior Minister said, baring his teeth and twitching his little moustache. He was inaugurating the Ghana Refu­gee and Immigration Service Boards.

He said some foreigners come in as tourists, investors, consultants, skilled workers or refugees. Others come as ‘charlatans, adventurers or plain criminals. “

Yes, there are many criminals among them. Our courts have tried a good number of them for fraud and misconduct.

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It is time we welcome only those who would come and invest or tour and go back peacefully and not those whose criminal intentions are well-hidden but get exposed in due course of time.

This article was first published on Saturday March 14, 1998

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 Decisions have consequences

 In this world, it is always important to recognise that every action or decision taken, has consequences.

It can result in something good or bad, depending on the quality of the decision, that is, the factors that were taken into account in the deci­sion making.

The problem with a bad decision is that, in some instances, there is no opportunity to correct the result even though you have regretted the decision, which resulted in the un­pleasant outcome.

This is what a friend of mine refers to as having regretted an unregreta­ble regret. After church last Sunday, I was watching a programme on TV and a young lady was sharing with the host, how a bad decision she took, had affected her life immensely and adversely.

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She narrated how she met a Cauca­sian and she got married to him. The white man arranged for her to join him after the marriage and process­es were initiated for her to join her husband in UK. It took a while for the requisite documentation to be procured and during this period, she took a decision that has haunted her till date.

According to her narration, she met a man, a Ghanaian, who she started dating, even though she was a mar­ried woman.

After a while her documents were ready and so she left to join her husband abroad without breaking off the unholy relationship with the man from Ghana.

After she got to UK, this man from Ghana, kept pressuring her to leave the white man and return to him in Ghana. The white man at some point became a bit suspicious and asked about who she has been talking on the phone with for long spells, and she lied to him that it was her cousin.

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Then comes the shocker. After the man from Ghana had sweet talked her continuously for a while, she decided to leave her husband and re­turn to Ghana after only three weeks abroad.

She said, she asked the guy to swear to her that he would take care of both her and her mother and the guy swore to take good care of her and her mother as well as rent a 3-bedroom flat for her. She then took the decision to leave her hus­band and return to Ghana.

She told her mum that she was re­turning to Ghana to marry the guy in Ghana. According to her, her mother vigorously disagreed with her deci­sion and wept.

She further added that her mum told her brother and they told her that they were going to tell her hus­band about her intentions.

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According to her, she threatened that if they called her husband to inform him, then she would commit suicide, an idea given to her by the boyfriend in Ghana.

Her mum and brother afraid of what she might do, agreed not to tell her husband. She then told her hus­band that she was returning to Ghana to attend her Grandmother’s funeral.

The husband could not understand why she wanted to go back to Ghana after only three weeks stay so she had to lie that in their tradition, grandchildren are required to be present when the grandmother dies and is to be buried.

She returned to Ghana; the flat turns into a chamber and hall accom­modation, the promise to take care of her mother does not materialise and generally she ends up furnishing the accommodation herself. All the promises given her by her boyfriend, turned out to be just mere words.

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A phone the husband gave her, she left behind in UK out of guilty conscience knowing she was never coming back to UK.

Through that phone and social media, the husband found out about his boyfriend and that was the end of her marriage.

Meanwhile, things have gone awry here in Ghana and she had regretted and at a point in her narration, was trying desperately to hold back tears. Decisions indeed have consequences.

NB: ‘CHANGE KOTOKA INTERNA­TIONAL AIRPORT TO KOFI BAAKO INTERNATIONAL AIRPORT’

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